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Throughout oocyte maturation, there is a simultaneous elevation in the concentrations of Ca²⁺ and Zn²⁺, and the fertilization-induced Ca²⁺ oscillations cease under Zn²⁺-deficient conditions, implying an interplay between these ions, potentially at the IP₃R1 level that harbors a Zn²⁺-binding domain.

The maintenance of proper mitochondrial-associated endoplasmic reticulum membranes is crucial for preventing skeletal muscle atrophy to interact with the Notch signaling pathway.

Phosphorylation of the pseudokinase Ulk4 by Stk36 promotes primary ciliary tip localization of both proteins to facilitate the phosphorylation and activation of Gli in response to Sonic hedgehog.

Although complete mouse in vitro spermatogenesis can be achieved, failure of adult Leydig cell development, with accumulation of progesterone and estradiol, androstenedione deficiency, deregulation of steroidogenic, and steroid target gene expression, were highlighted in organotypic cultures, even with hCG.

Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for members of the Groucho/TCF repressive complex in maintaining non-invasive cell fate in C. elegans.

Imaging experiments reveal the complex and dynamic nature of the transcriptional hubs associated with Notch signaling.

Cylicin 1 and Cylicin 2 are essential components of the sperm perinuclear theca and their loss results in impaired spermiogenesis and thus in infertility in mice and men.

On different bacterial diets, which also serve as different environments for Caenorhabditis elegans, specific sensory neurons and insulin-like peptides integrate food-derived signals to modulate oocyte biology, and hence reproduction.

The accumulation of ferroptotic stress during tooth development has a critical effect on its morphogenesis.