Browse our latest Developmental Biology articles

Combined single nucleus RNAseq and ATACseq enabled the first molecular resolution of all hindbrain rhombomeres, the derivation of a unique gene regulatory network for each rhombomere, and the identification of gene expression changes as rhombomeres form from early progenitor pools.

Single-cell transcriptome analyses during cortical brain development in ferrets and its comparison with public human datasets reveal that there are common progenitors and lineages among gyrencephalic mammalian brain development.

Single-cell transcriptome analysis of the regenerating retina in adult zebrafish reveals molecular control steps during Müller glia stem cell activation, progressive differentiation, and neural regeneration.

Research on heart tube assembly using zebrafish reveals a pivotal role for intrinsic Pdgfra–PI3K signaling in steering the movement of the myocardium and polarizing myocardial cell protrusions.

The Foxa2 lineage-based organ generative strategy allows us to establish a unique paradigm for the simultaneous generation of functional whole lungs and thymus, which can be applied to future transplantation therapy.

Mutant and gene expression analyses shows that phytohormones and mobile transcription factors interact to coordinate organ formation with stem cell maintenance in the plant shoot meristem.

Isl2 orchestrates specific hindlimb motor pool arrangement, guaranteeing accurate motor control and sensorimotor circuit functionality.

Genetic birthdating in forebrain organoids shows asymmetric inheritance of centrosomes in human neural progenitor cells, required for proper human neurogenesis.

TF-DNA binding regulates spatial and temporal gene expression and drives robust pattern formation by modulating transcriptional kinetics via cooperative interactions among weak TF binding sites and tuning bursting rates by reducing the time spent in the ON state.

Single-cell transcriptome analysis of sacral compared with vagal neural crest-derived cells in the developing chick enteric nervous system reveals both similarities and differences between these two cell populations.