Interest in the ecology, biology and evolution of amphioxus is growing, and the availability of several species is helping to improve our understanding of chordate evolution.
A novel mechanism of gene regulation is discovered wherein a specific long non-coding RNA abolishes the blocking activity of chromatin insulator in the Drosophila HOX gene cluster.
An unexpected interaction between a long non-coding RNA locus and a genetic insulator called Fub-1 has an important role in gene regulation during development in Drosophila.
Pankaj Sahai-Hernandez, Claire Pouget ... David Traver
A rare population of endothelial cells emerges from a bipotent muscle progenitor population in the paraxial mesoderm and provides niche support to induce hematopoietic stem cells.
Genetic interaction and biochemical analyses have unveiled the crucial involvement of CTPS in the regulation of adipocyte growth, lipid metabolism, and metabolic adaptation in Drosophila, achieved through activating the PI3K-Akt-SREBP pathway.
ECM-Itgb1 signaling and cell-cell adhesion are pivotal and coordinate together to regulate pancreatic islet aggregation, architecture, and functional maturation during development.
Organoids are useful in studying guidance cues for retinal ganglion cell (RGC) axon generation and regeneration, and the method of RGC isolation via CNTN2 facilitates investigating RGC-related retinal diseases such as glaucoma.
Valeria Scagliotti, Maria Lillina Vignola ... Marika Charalambous
Pituitary gland size and stem cell number is modulated during early life in the mouse by the imprinted gene Dlk1, which acts in multiple developmental compartments in a dosage-sensitive manner.
