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    1. Medicine
    2. Neuroscience

    Cold induces brain region-selective neuronal activity-dependent lipid metabolism

    Hyeonyoung Min, Yale Y Yang, Yunlei Yang
    Not revised
    Reviewed Preprint v1
    1. Medicine

    Phosphate as an adjunct to calcium in promoting coronary vascular calcification in chronic inflammatory states

    Gordon L Klein
    Phosphate and calcium from resorbing bone can find their way to the coronary circulation and contribute to atherosclerotic calcification of the blood vessels.
    1. Computational and Systems Biology
    2. Medicine

    Single-cell transcriptome analysis of cavernous tissues reveals the key roles of pericytes in diabetic erectile dysfunction

    Seo-Gyeong Bae, Guo Nan Yin ... Jihwan Park
    Single-cell RNA sequencing analysis of diabetic mouse cavernous tissue revealed that LBH is a novel pericyte marker and may interact with Crystallin Alpha B and Vimentin to promote neurovascular regeneration.
    1. Medicine
    2. Neuroscience

    Digital wearable insole-based identification of knee arthropathies and gait signatures using machine learning

    Matthew F Wipperman, Allen Z Lin ... Olivier Harari
    Biosensor data collected by digital insoles is comparable to lab-based clinical assessments and can be used to identify subject-specific gait patterns.
    1. Medicine
    2. Microbiology and Infectious Disease

    Neuroinfectiology of an atypical anthrax-causing pathogen in wild chimpanzees

    Tobias Gräßle, Carsten Jäger ... Markus Morawski
    Not revised
    Reviewed Preprint v1
    1. Medicine

    Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis

    Wei Chen, Yun Lu ... Yi-Ping Li
    Low expression of Cbfb may be the cause of osteoarthritis, and local admission of Cbfb may rescue and protect against osteoarthritis through decreasing Wnt/β-catenin signaling, and increasing Hippo/Yap signaling and Tgfβ/Smad2/3 signaling in osteoarthritis articular cartilage.
    1. Genetics and Genomics
    2. Medicine

    Impaired central pattern generators due to abnormal EPHA4 signaling leads to idiopathic scoliosis

    Lianlei Wang, Sen Zhao ... Nan Wu
    Not revised
    Reviewed Preprint v1
    1. Medicine
    2. Neuroscience

    Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

    Yunlu Xue, Yimin Zhou, Constance L Cepko
    Multiple alleles of Txnip, which can interact with several different proteins, including Hsp90AB1, were tested for their ability to prolong the survival of cone photoreceptors in diseases leading to blindness.
    1. Medicine

    Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility

    Shahriar Mowla, Linda Farahani ... Channa N Jayasena
    Not revised
    Reviewed Preprint v1
    1. Medicine

    Fungal–bacteria interactions provide shelter for bacteria in Caesarean section scar diverticulum

    Peigen Chen, Haicheng Chen ... Xing Yang
    Local abnormal fungi in Caesarean section scar diverticulum can affect the abundance of bacteria through specific metabolites, thereby destroying the stability of bacteria and the entire microbial community.
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