Editors for Structural Biology and Molecular Biophysics
Senior editors
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Amy H Andreotti
Iowa State University, United States
Amy Andreotti is the Roy J Carver Chair in Biochemistry and a University Professor at Iowa State University. She joined the faculty of the Roy J Carver Department of Biochemistry, Biophysics and Molecular Biology in 1997 after earning her PhD in Chemistry at Princeton University and completing a postdoctoral training period in the Chemistry Department at Harvard University where she was a Science Scholar at the Bunting Institute of Radcliffe College. Her work explores the mechanisms of kinase regulation during cell signaling with an emphasis on the immune specific TEC family of non-receptor tyrosine kinases. A particular focus of the lab is Bruton’s tyrosine kinase (BTK) and its interactions with small molecule therapeutics. Her lab uses a variety of biochemical, enzymatic and structural biology methods including solution NMR spectroscopy.
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- NMR spectroscopy
- kinase regulation
- cell signalling
- Tec family kinases
- Experimental organism
- human
- Competing interests statement
- Amy Andreotti's research is currently funded by the National Institutes of Health. She also serves on the National Advisory Committee for the Biomedical Scholars program of the Pew Charitable Trusts.
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Felix Campelo
The Institute of Photonic Sciences, Spain
Felix Campelo is a researcher specializing in membrane biophysics, cell biology, and fluorescence microscopy tools to understand intracellular organization. He did his PhD research in theoretical biophysics at the University of Barcelona and Tel Aviv University, developing computational and theoretical methods to study membrane shape and dynamics. In his postdoc at the Malhotra lab (CRG-Center for Genomic Regulation), he shifted to experimental cell biology and biochemistry to explore mechanisms of intracellular trafficking and the cooperation between lipids and proteins in organizing Golgi membranes.
Currently leading the Intracellular Dynamics and Nanoscopy lab at ICFO-The Institute of Photonic Sciences in Barcelona, Felix and his interdisciplinary lab focus on organelle morphology and dynamics, with a particular interest in intracellular membrane trafficking in the early secretory pathway. They employ advanced microscopy techniques, molecular and cell biology tools, and theoretical biophysics to address fundamental topics in cell biology.
- Expertise
- Physics of Living Systems
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- membrane mechanics
- membrane curvature
- intracellular trafficking
- membrane organization
- membrane contact sites
- Golgi complex
- endoplasmic reticulum exit sites
- super-resolution microscopy
- single-molecule microscopy
- Experimental organism
- human
- S. cerevisiae
- Competing interests statement
- Dr Campelo receives funding from Government of Spain, Fundació Privada Cellex, Fundació Privada Mir-Puig, and Generalitat de Catalunya.
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Qiang Cui
Boston University, United States
Qiang Cui is a professor of Chemistry at Boston University and also affiliated with the Departments of Physics and Biomedical Engineering. He received a B.S. in Chemical Physics from the University of Science and Technology of China in 1993, and a Ph.D. in Theoretical Chemistry in 1997 from Emory University under the tutelage of Professor Keiji Morokuma. He conducted postodctoral research with Professor Martin Karplus at Harvard University and, in 2001, moved to the University of Wisconsin, Madison, as a faculty member in the Chemistry department. After spending almost 17 wonderful years in Madison, he moved back to Boston in 2018. His current research interests include quantum chemistry and statistical mechanics and their applications to various chemical, biological, and materials problems.
Expertise: Computational biophysics, especially molecular dynamics, hybrid quantum mechanical/molecular mechanics simulations, free energy simulations applied to enzymes, biomolecular machines and lipid membranes.
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular dynamics
- hybrid quantum
- classical simulations
- enzyme catalysis
- allostery
- protein dynamics
- membrane remodeling
- Competing interests statement
- Qiang Cui currently serves as an associate editor for the Journal of Chemical Theory and Computation (American Chemical Society).
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Volker Dötsch
Goethe University, Germany
Volker Dötsch is Professor of Biophysical Chemistry at Goethe University and a member of the Magnetic Resonance Center Frankfurt. He studied chemistry at the University of Göttingen and obtained a PhD from the ETH in Zürich. As a postdoctoral fellow he used NMR to determine the structure of protein-DNA complexes at the Harvard Medical School. In 1998 he moved as assistant professor to the University of California San Francisco (UCSF). In 2003 he was appointed professor at the Institute of Biophysical Chemistry of Goethe University in Frankfurt. His research interests focus on the structural and functional characterization of members of the p53 protein family, in particular p63 and its involvement in genetic quality control in germ cells. In addition, his laboratory uses a combination of NMR spectroscopy and cell-free protein expression to investigate the structure and function of membrane proteins and studies molecular interactions regulating autophagy. His lab uses a wide variety of biophysical methods including NMR spectroscopy and combines these studies with investigations in cell culture experiments and mouse models. Volker Dötsch is an elected EMBO member.
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- p53 protein family
- cell-free expression and membrane protein structure and function
- autophagy
- Competing interests statement
- Volker Dötsch has received funding from the Deutsche Forschungsgemeinschaft, the National Institutes of Health and the Deutsche Krebshilfe. He is on the Scientific Advisory Board of the Frankfurt Institute of Advanced Studies and a member of the editorial boards of Journal of Biological Chemistry and Cell Death & Disease.
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Merritt Maduke
Stanford University School of Medicine, United States
Merritt Maduke is an Associate Professor of Molecular & Cellular Physiology and co-director of the Neurosciences Interdisciplinary Graduate Program at Stanford University School of Medicine. She received her PhD in Chemistry from the University of California, San Diego and did postdoctoral training at Brandeis University with Professor Chris Miller. Her research at Stanford is centered on the biophysics of ion channels and transporters, with the overarching goal of understanding molecular mechanisms within the context of physiological functions. She also applies her mechanistic approach in the field of ultrasound neuromodulation. She was awarded the Society of General Physiologist’s Cranefield Award for her research on ion channels (2008) and served as the Society’s President from 2018-2019.
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Biochemistry and Chemical Biology
- Research focus
- ion channel and transporter molecular mechanisms
- ion channel and transporter physiology
- ion channel and transporter pharmacology
- ultrasound neuromodulation
- Experimental organism
- E. coli
- mouse
- rat
- Competing interests statement
- Merritt Maduke is employed by Stanford University and receives research funding from the National Institutes of Health and Stanford Innovative Medicine Accelerator. She has served on the BPNS and BBM study sections at the NIH and as ad hoc member of additional panels. She serves on the editorial boards of the Biophysical Journal and The Journal of General Physiology and is a founding curator for Biophysics Colab.
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Kenton J Swartz
National Institute of Neurological Disorders and Stroke, NIH, United States
Kenton Swartz has been a Senior Investigator in the National Institute of Neurological Disorders and Stroke within the National Institutes of Health in Bethesda, Maryland since 2003. He obtained a BS in Chemistry and Biology from Eastern Mennonite College in 1986 and a PhD in Neurobiology from Harvard Medical School in 1993, where he worked with Bruce Bean studying the regulation of voltage-gated calcium channels by G-proteins and protein kinases. He obtained postdoctoral training with Roderick MacKinnon at Harvard Medical School, where he began isolating and studying toxins that interact with voltage-activated potassium channels. His laboratory uses biochemical, molecular biological, biophysical and structural techniques to understand how ion channel proteins sense critical biological stimuli, including membrane voltage, temperature, and both chemical and mechanical signals. He received an NIH Directors Award for Scientific Achievement in 2008, an NIH Office of the Director Honor Award on behalf of the Diversity Task Force in 2011 and the Kenneth S. Cole Award from the Biophysical Society in 2017. He has also served as the president of the Society of General Physiologists.
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Biochemistry and Chemical Biology
- Research focus
- ion channel structure
- ion channel mechanisms
- ion channel physiology
- ion channel pharmacology
- Experimental organism
- mouse
- Competing interests statement
- Kenton Swartz is employed by the Intramural Research Program of the National Institute of Neurological Disorders and Stroke, National Institutes of Health. In addition to serving as a Senior Editor at eLife, he has served as a Reviewing Editor for eLife and as an Associate Editor at the Journal of General Physiology. He also teaches yoga at LifeTime Athletic.
Reviewing editors
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Sameh Ali
Children's Cancer Hospital Egypt, Egypt
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Cell Biology
- Immunology and Inflammation
- Neuroscience
- Structural Biology and Molecular Biophysics
- Research focus
- metabolism
- mitochondria
- redox biology
- reactive oxygen species
- membrane biophysics
- inflammation
- aging
- oncology
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Toby W Allen
RMIT University, Australia
- Expertise
- Structural Biology and Molecular Biophysics
- Physics of Living Systems
- Neuroscience
- Research focus
- computational biophysics
- molecular dynamics
- free-energy calculations
- ion channels
- ion permeation
- membranes
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Patricia Bassereau
Institut Curie, France
- Expertise
- Cell Biology
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- physics of cells
- membrane biophysics
- mechanobiology
- intracellular traffic
- endocytosis
- adhesion
- cellular protrusions
- biomimetic membranes
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Kurt Beam
University of Colorado Anschutz Medical Campus, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Physics of Living Systems
- Research focus
- excitation-contraction coupling in skeletal muscle
- voltage-gated calcium channels
- calcium release channels
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Amie K Boal
Pennsylvania State University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- bioinorganic chemistry
- enzymes
- microbial chemistry
- x-ray crystallography
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Axel T Brunger
Stanford University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- neurotransmission
- membrane fusion
- X-ray crystallography
- electron microscopy
- macromolecular computer simulation
- Experimental organism
- mouse
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Anne E Carlson
University of Pittsburgh, United States
- Expertise
- Developmental Biology
- Structural Biology and Molecular Biophysics
- Research focus
- fertilization
- ion channel regulation
- biophysics
- sperm
- calcium
- eggs
- zinc
- TMEM16A
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Sandipan Chowdhury
University of Iowa, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- physiology
- biophysics
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Rosana Collepardo
University of Cambridge, United Kingdom
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- epigenetic phenomena
- DNA structure
- gene expression
- molecular modeling
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Mauricio Comas-Garcia
Universidad Autónoma de San Luis Potosí, Mexico
- Expertise
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Research focus
- physical virology
- RNA packaging
- viral assembly
- virus-like-particle
- vaccines
- RNA viruses
- structural virology
- biophysics
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Laszlo Csanady
Semmelweis University, Hungary
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- ion channel structure-function
- CFTR
- TRPM2
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Laura R Delgui
National Scientific and Technical Research Council, Argentina
- Expertise
- Cell Biology
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Research focus
- virus-host cell interactions
- membranes
- molecular biology
- cellular biology
- structural biology
- biophysics
- molecular dynamics
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Matthias Elgeti
Leipzig University, Germany
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- spectroscopy
- membrane proteins
- electron paramagnetic resonance
- G protein-coupled receptors (GPCR)
- G proteins
- arrestin
- integrative structural biology
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Carlos Escande
Institut Pasteur de Montevideo, Uruguay
- Expertise
- Medicine
- Structural Biology and Molecular Biophysics
- Research focus
- atherosclerosis
- inflammatory diseases
- metabolism
- obesity
- type 2 diabetes
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Aaron Frank
Arrakis Therapeutics, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- molecular modeling
- biophysics
- structural biology
- computation
- RNA biochemistry
- RNA structural biology
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Adam Frost
University of California, San Francisco, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- cryo-EM
- electron cryo-microscopy
- membranes
- membrane remodeling
- proteostasis
- stress responses
- translation
- mitochondria
- nuclear envelope
- intracellular trafficking
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Teresa Giraldez
Universidad de La Laguna, Spain
- Expertise
- Neuroscience
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- neuronal excitability
- channelopathies
- Experimental organism
- mouse
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Marcel Goldschen-Ohm
University of Texas at Austin, United States
- Expertise
- Neuroscience
- Structural Biology and Molecular Biophysics
- Research focus
- ion channel structure and mechanisms
- single molecule dynamics
- single molecule fluorescence
- patch-clamp electrophysiology
- ligand binding
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Martin Graña
Institut Pasteur de Montevideo, Uruguay
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Evolutionary Biology
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- protein 3D structure
- structural bioinformatics
- structure/function relationships
- evolution
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Nikolaus Grigorieff
Janelia Research Campus, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- cryo-EM methods
- image processing
- algorithms
- molecular mechanisms
- Experimental organism
- S. cerevisiae
- rotavirus
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Yogesh K Gupta
The University of Texas Health Science Center at San Antonio, United States
- Expertise
- Medicine
- Structural Biology and Molecular Biophysics
- Cancer Biology
- Microbiology and Infectious Disease
- Research focus
- drug discovery
- nucleic acid modifications
- cancer epigenetics
- structures of viral proteins
- host-pathogen interactions
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Shozeb Haider
University College London, United Kingdom
- Expertise
- Medicine
- Structural Biology and Molecular Biophysics
- Computational and Systems Biology
- Microbiology and Infectious Disease
- Research focus
- X-ray crystallography
- molecular dynamics simulations
- allostery
- structure-based drug design
- structural bioinformatics
- computational chemistry
- nucleic acids
- rare diseases
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Donald Hamelberg
Georgia State University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- molecular dynamics
- classical simulations
- protein dynamics
- protein allostery
- enzyme catalysis
- Long time scale dynamics
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Heedeok Hong
Michigan State University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- membrane proteins
- membrane protein folding
- membrane protein stability
- rhomboid proteases
- ATP-dependent proteolysis
- AAA+
- GlpG
- FtsH
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Leon D. Islas
Universidad Nacional Autónoma de México, Mexico
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- molecular computation
- membrane protein
- ion channels
- fluorescence
- models
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John Janetzko
University of Colorado Anschutz Medical Campus, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- GPCRs
- cryo-EM
- X-ray crystallography
- Single-molecule FRET
- mass spectrometry
- phosphoinositide signaling
- post translational modifications
- glycosyltransferases
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Andres Jara-Oseguera
University of Texas at Austin, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- ion channels
- Transient Receptor Potential (TRP) channels
- membrane transport proteins
- nociception
- voltage-activated channels
- cellular excitability
- pain-signaling
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Joanne Lemieux
University of Alberta, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protease
- intramembrane protease
- crystallography
- membrane proteins
- structural biology
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Richard Lewis
Stanford University School of Medicine, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- calcium signaling
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Chang Liu
Johns Hopkins University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Microbiology and Infectious Disease
- Research focus
- coronavirus
- cryo-EM
- viral replication
- transcriptional regulation
- virus-host interactions
- RNA structure and processing
- ribonucleoprotein complex
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Andrei Lupas
Max Planck Institute for Developmental Biology, Germany
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Structural Biology and Molecular Biophysics
- Evolutionary Biology
- Research focus
- bacterial surface proteins
- bioinformatics
- coiled coils
- protein design
- protein evolution
- protein structure
- transmembrane signal tranduction
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Fabrizio Marinelli
Medical College of Wisconsin, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- computational biophysics
- molecular dynamics
- membrane proteins
- membrane transporters
- ion channels
- membrane remodeling
- integrative structural biology
- computational methods development
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Mark T. Nelson
The University of Vermont, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- ion channels
- calcium signaling
- neurovascular coupling in the brain
- vascular, cell and systems biology
- Experimental organism
- mouse
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Hannes Neuweiler
University of Würzburg, Germany
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- protein folding
- protein dynamics
- protein engineering
- fluorescence spectroscopy
- fluorescence probes
- kinetics
- single-molecule fluorescence spectroscopy
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Candie Paulsen
Yale University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- ion channels
- TRP channels
- ligand-gated ion channels
- calcium regulation
- membrane protein structural biology
- cryo-EM of ion channels and membrane proteins
- pain signaling
- redox biology
- signal transduction
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Camilo Perez
University of Georgia, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- membrane proteins
- transporters
- structural biology
- bacteria
- cell wall
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Stephan Pless
University of Copenhagen, Denmark
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- ion channels
- pharmacology
- electrophysiology
- biophysics
- chemical biology
- non-canonical amino acids
- protein engineering
- neurobiology
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Kate Poole
UNSW Sydney, Australia
- Expertise
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- mechanobiology
- mechanosensitive ion channels
- patch-clamp electrophysiology
- ion channels
- microgravity
- cellular force sensing
- atomic force microscopy
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Owen Pornillos
University of Virginia, United States
- Expertise
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- higher-order assembly
- cell-free reconstitution
- retrovirus structure
- tripartite motif proteins
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Murali Prakriya
Northwestern University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- cell imaging
- cellular electrophysiology
- calcium signaling
- ion channels
- neurobiology
- cell physiology
- Experimental organism
- mouse
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Catherine Proenza
University of Colorado Anschutz Medical Campus, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Physics of Living Systems
- Research focus
- electrophysiology
- cardiac pacemaking
- ion channels
- molecular biophysics
- HCN channels
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Julien Roche
Iowa State University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- protein folding
- intrinsically disordered proteins
- solution NMR spectroscopy
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Rina Rosenzweig
Weizmann Institute of Science, Israel
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- NMR
- protein folding
- chaperones
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Jon T Sack
University of California, Davis, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- ion channels
- voltage gating
- voltage clamp electrophysiology
- ligand binding
- allostery
- rate theory modeling
- thermodynamics
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Rajan Sankaranarayanan
CSIR – Centre for Cellular and Molecular Biology, India
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- crystal structure
- mechanism
- translation of genetic code
- proofreading
- editing
- tRNA synthetase
- Experimental organism
- E. coli
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Sjors HW Scheres
Medical Research Council Laboratory of Molecular Biology, United Kingdom
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- cryo-EM
- maximum likelihood
- image processing
- amyloids
- tau
- alpha-synuclein
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Sang-Hee Shim
Korea University, South Korea
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- super-resolution optical microscopy
- in situ structural biology
- multiplexed microscopy
- spatial genome organization and dynamics
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Show-Ling Shyng
Oregon Health and Science University, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- protein structure-function
- electrophysiology
- pharmacology
- intracellular trafficking
- signal transduction
- chaperones
- islet biology
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Jungsan Sohn
Johns Hopkins University School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Immunology and Inflammation
- Microbiology and Infectious Disease
- Research focus
- innate immunity
- inflammasomes
- X-ray crystallography
- cryo-EM
- biochemistry
- enzyme kinetics
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Alan Talevi
National University of La Plata, Argentina
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Microbiology and Infectious Disease
- Structural Biology and Molecular Biophysics
- Research focus
- bioinformatics
- drug discovery
- cheminformatics
- pharmacy
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Lipi Thukral
CSIR-Institute of Genomics and Integrative Biology, India
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- computational structural biology
- molecular dynamics simulations
- protein-lipid interactions
- vesicles
- membranes
- autophagy
- structural genomics
- protein crowding
- spike protein
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Mohamed Trebak
University of Pittsburgh School of Medicine, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Cell Biology
- Biochemistry and Chemical Biology
- Research focus
- calcium channels
- receptor signalling
- ion channel regulation
- vascular remodeling
- smooth muscle
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Julie P I Welburn
University of Edinburgh, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- mitosis
- cytoskeleton
- motors
- phosphorylation
- kinase
- microtubule
- cilia
- kinetochore
- Experimental organism
- human
- in vitro
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Jie Xiao
Johns Hopkins University, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Chromosomes and Gene Expression
- Microbiology and Infectious Disease
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- single molecule biophysics
- microbiology
- cell division
- cell wall
- gene expression
- Experimental organism
- E. coli
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Bin Zhang
Massachusetts Institute of Technology, United States
- Expertise
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- computational biophysics
- molecular dynamics
- chromatin organization
- biomolecular condensates
- genome folding
- coarse graining
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Lejla Zubcevic
University of Kansas Medical Center, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- membrane transport
- structural biology
