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    1. Biochemistry and Chemical Biology

    Study suggests stalled amyloid protein production drives Alzheimer’s disease

    A study of rare familial genetic mutations linked to early-onset dementia supports the idea that stalled protein processing contributes to Alzheimer’s disease.

  2. eLife appoints Timothy Behrens as Editor-in-Chief

    Behrens will lead eLife’s efforts to improve research communication for all.

  3. Media Coverage: December roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in December 2024, including Asia Research News, The New York Times and La Gaceta.
    1. Plant Biology

    Parasite ‘matchmakers’ genetically alter plant cells to attract insects

    Researchers have revealed how parasitic phytoplasmas manipulate plant biology to act as matchmakers, boosting male insect appeal by modulating hosts to attract more reproductive females.
    1. Genetics and Genomics

    Gene discovery sheds light on common ear condition in people with Down syndrome

    The gene DYRK1A could be a potential therapeutic target to treat ‘glue ear’ in people with Down syndrome, according to a new study.

  6. Media Coverage: November roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in November 2024, including Asia Research News, LiveScience and Earth.com.

  7. Media Coverage: October roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in October 2024, including Earth.com, StudyFinds and Cosmos Magazine.
    1. Neuroscience

    Researchers identify new therapeutic strategy for fentanyl overdose

    Blocking peripheral opioid receptors with naloxone methiodide sufficiently prevents and reverses fentanyl-induced cardiorespiratory depression without causing the aversive effects of naloxone in rodents.
    1. Stem Cells and Regenerative Medicine

    Study reveals breakthrough in reversing age-related decline in bone healing

    Combining intermittent fasting with localised Wnt3a treatments can rejuvenate bone repair in older mice, offering hope for reversing age-related tissue decline.
    1. Microbiology and Infectious Disease

    Study shows how genetic defects in Toxoplasma are rescued by co-infection

    Toxoplasma gondii parasites can use secreted factors to compensate for genetic defects in neighbouring parasites, highlighting a limitation of pooled CRISPR screens.
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