Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Microbiology and Infectious Disease

    Virus adaptation to heparan sulfate comes with capsid stability tradeoff

    Han Kang Tee, Simon Crouzet ... Caroline Tapparel
    1. Medicine
    2. Microbiology and Infectious Disease

    The effect of combining antibiotics on resistance: A systematic review and meta-analysis

    Berit Siedentop, Viacheslav N Kachalov ... Sebastian Bonhoeffer
    A systematic review shows no evidence of harm or benefit of antibiotic combinations on resistance evolution as clinical data lack statistical power to draw definitive conclusions, highlighting a knowledge gap.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Antimicrobial activity of iron-depriving pyoverdines against human opportunistic pathogens

    Vera Vollenweider, Karoline Rehm ... Rolf Kümmerli
    Iron-chelating pyoverdines from environmental Pseudomonas spp. show promising antibacterial activity against key human pathogens through the induction of iron starvation, while associated toxicity for host systems remains low.
    1. Microbiology and Infectious Disease

    Salmonella-induced SIRT1 and SIRT3 are crucial for maintaining the metabolic switch in bacteria and host for successful pathogenesis

    Dipasree Hajra, Raju S Rajmani ... Dipshikha Chakravortty
    SIRT1 and SIRT3-mediated immunometabolic shift governs intracellular Salmonella proliferation both in vitro and in vivo and dissemination in mice, thereby influencing the infection outcomes.
    1. Microbiology and Infectious Disease

    An improved bacterial single-cell RNA-seq reveals biofilm heterogeneity

    Xiaodan Yan, Hebin Liao ... Yingying Pu
    RiboD-PETRI, a cost-effective, equipment-free plate-based scRNA-seq technique that integrates a unique bacterial rRNA depletion protocol, significantly enhancing mRNA detection rate and revealing within-population heterogeneity, offering valuable insights for research applications.
    1. Microbiology and Infectious Disease

    Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis

    Nelson V Simwela, Eleni Jaecklein ... David G Russell
    Not revised
    Reviewed Preprint v1
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Livestock abortion surveillance in Tanzania reveals disease priorities and importance of timely collection of vaginal swab samples for attribution

    Felix Lankester, Tito J Kibona ... Sarah Cleaveland
    Livestock abortion surveillance can capture valuable information on important livestock pathogens, including those that are zoonotic and with epidemic potential, revealing importance of timely collection of diagnostic samples for attribution.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Genomic and structural insights into Jyvaskylavirus, the first giant virus isolated from Finland

    Gabriel Magno de Freitas Almeida, Miika Leppänen ... Lotta-Riina Sundberg
    Not revised
    Reviewed Preprint v1

Senior editors

  1. Diane M Harper
    University of Michigan, United States
  2. Bavesh Kana
    University of the Witwatersrand, South Africa
  3. John W Schoggins
    University of Texas Southwestern Medical Center, United States
  4. See more editors