Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    A General Mechanism for Initiating the General Stress Response in Bacteria

    Rishika Baral, Kristin Ho ... Niels Bradshaw
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Control of pili synthesis and putrescine homeostasis in Escherichia coli

    Iti Mehta, Jacob B Hogins ... Larry Reitzer
    Putrescine has a homeostatic network that controls pili synthesis and energy metabolism.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Single-cell RNA-seq reveals trans-sialidase-like superfamily gene expression heterogeneity in Trypanosoma cruzi populations

    Lucas Inchausti, Lucía Bilbao ... Pablo Smircich
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Solid
    1. Microbiology and Infectious Disease

    Heat Stress Induced Bacterial Tolerance against Phage Facilitates the Evolution of Resistance

    Fan Zhang, Hao-Ze Chen ... Liu Jiafeng
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    Estimation of Rotavirus Vaccine Effectiveness Based on Whole Genome Sequences

    Jiye Kwon, Jose Jaimes ... Virginia E Pitzer
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Nora virus proliferates in dividing intestinal stem cells and sensitizes flies to intestinal infection and oxidative stress

    Adrien Franchet, Samantha Haller ... Dominique Ferrandon
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages

    Ainhoa Arbués, Sarah Schmidiger ... Damien Portevin
    Genetically diverse Mycobacterium tuberculosis complex strains induce a gamut of human granulomatous responses in vitro, with a role for IL-1β in aggregate formation.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase

    Eva Herdering, Tristan Reif-Trauttmansdorff ... Ruth Anne Schmitz
    The central nitrogen-metabolite 2-oxoglutarate directly promotes glutamine synthetase activity by inducing its dodecameric assembly and priming the active sites, representing a novel mechanism of regulation.
    1. Microbiology and Infectious Disease

    Architecture of genome-wide transcriptional regulatory network reveals dynamic functions and evolutionary trajectories in Pseudomonas syringae

    Yue Sun, Jingwei Li ... Xin Deng
    The genome-wide transcriptional regulatory network in Pseudomonas syringae demonstrates the regulatory diversity and functional pathways.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

    Marisa S Egan, Emily A O'Rourke ... Sunny Shin
    Analysis of inflammasome responses in human macrophages reveals that inflammatory caspases and pyroptotic factors control Salmonella replication primarily within the cytosol and also within vacuoles.
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Highlights

    1. Microbiology and Infectious Disease

    Malaria: explore our collection of articles

    Edited by Olivier Silvie et al.
    1. Epidemiology and Global Health
    2. Medicine
    3. Microbiology and Infectious Disease

    COVID-19: A collection of articles

    Edited by Diane M Harper et al.
    1. Microbiology and Infectious Disease
    computer screen covered in numbers

    Applying deep learning to the microbiome – explore the public reviews of this recent preprint

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Bavesh Kana
    University of the Witwatersrand, South Africa
  3. Joshua T Schiffer
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors