Immunology and Inflammation

Immunology and Inflammation

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Nora virus proliferates in dividing intestinal stem cells and sensitizes flies to intestinal infection and oxidative stress

    Adrien Franchet, Samantha Haller ... Dominique Ferrandon
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    Trained innate immunity attenuates macrophage efferocytosis of cancer cells

    Alexandros Chatzis, Jakub Lukaszonek ... Ioannis Kourtzelis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation

    Single-cell transcriptomics identifies a dampened neutrophil function and accentuated T-cell cytotoxicity in tobacco flavored e-cigarette exposed mouse lungs

    Gagandeep Kaur, Thomas Lamb ... Irfan Rahman
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    The C3-C3aR axis modulates trained immunity in alveolar macrophages

    Alexander P Earhart, Rafael Aponte Alburquerque ... Hrishikesh S Kulkarni
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    • Incomplete
    1. Immunology and Inflammation

    Inflammasomes: A tale of two caspases

    Denise M Monack
    Macrophages control intracellular pathogens like Salmonella by using two caspase enzymes at different times during infection.
    Version of Record
    Insight
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Soluble immune mediators orchestrate protective in vitro granulomatous responses across Mycobacterium tuberculosis complex lineages

    Ainhoa Arbués, Sarah Schmidiger ... Damien Portevin
    Genetically diverse Mycobacterium tuberculosis complex strains induce a gamut of human granulomatous responses in vitro, with a role for IL-1β in aggregate formation.
    1. Immunology and Inflammation
    2. Medicine

    Deciphering the preeclampsia-specific immune microenvironment and the role of pro-inflammatory macrophages at the maternal–fetal interface

    Haiyi Fei, Xiaowen Lu ... Lingling Jiang
    Multi-omics analysis shows that preeclampsia-specific immune cell network was regulated by Folr2+Ccl7+Ccl8+C1qa+C1qb+C1qc+ pro-inflammatory macrophages, which can induce the CD8+ and Th17 memory T cells generation while inhibiting the gMDSCs production.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages

    Marisa S Egan, Emily A O'Rourke ... Sunny Shin
    Analysis of inflammasome responses in human macrophages reveals that inflammatory caspases and pyroptotic factors control Salmonella replication primarily within the cytosol and also within vacuoles.
    1. Immunology and Inflammation

    Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations

    Sébastien de La Forest Divonne, Juliette Pouzadoux ... Emmanuel Vignal
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation

    MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles

    Linsey JF Peters, Leonida Rakateli ... Emiel PC van der Vorst
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
Load more

Highlights

    1. Immunology and Inflammation

    Inflammasomes versus Salmonella

    Denise M Monack
    1. Developmental Biology
    2. Immunology and Inflammation

    A hemocyte atlas for an insect

    Samuel Liegeois, Dominique Ferrandon
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    The immune basis of disease susceptibility

    Ruy M Ribeiro, Luis Graca

Senior editors

  1. Betty Diamond
    The Feinstein Institute for Medical Research, United States
  2. Diane M Harper
    University of Michigan, United States
  3. Tony Ng
    King's College London, United Kingdom
  4. See more editors