Developmental Biology

Latest articles

1. 1. Developmental Biology
   2. Stem Cells and Regenerative Medicine

   A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro

   Paolo Petazzi, Telma Ventura ... Antonella Fidanza

   A novel tool is used to assess gene function in vitro by targeted endogenous transcriptional activation to unveil novel players in development and disease.
2. 1. Developmental Biology

   Basement membranes are crucial for proper olfactory placode shape, position and boundary with the brain, and for olfactory axon development

   Pénélope Tignard, Karen Pottin ... Marie Anne Breau

   Laminin gamma1-dependent basement membranes are required for multiple aspects of olfactory system development in zebrafish, including the maintenance of placode tissue shape and the growth of the olfactory axons.
3. 1. Developmental Biology

   The evolutionary modifications of a GoLoco motif in the AGS protein facilitate micromere formation in the sea urchin embryo

   Natsuko Emura, Florence DM Wavreil ... Mamiko Yajima

   Activator of G-protein signaling C-terminus serves as a variable element to induce asymmetric cell division, facilitating developmental diversity among species.
4. 1. Developmental Biology

   Brain Development: Single cells tell it all

   Margaret Hines, Elias Oxman ... Irene Zohn

   A new single-cell atlas of gene expression provides insights into the patterning of the neural plate of mice.
5. 1. Cell Biology
   2. Developmental Biology

   Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

   Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan
6. 1. Developmental Biology

   Neuroprotective role of Hippo signaling by microtubule stability control in C. elegans

   Hanee Lee, Junsu Kang ... Junho Lee
7. 1. Developmental Biology
   2. Computational and Systems Biology

   Dorsal/NF-κB exhibits a dorsal-to-ventral mobility gradient in the Drosophila embryo

   Hadel Al Asafen, Natalie M Clark ... Gregory T Reeves
8. 1. Developmental Biology
   2. Physics of Living Systems

   The geometric basis of epithelial convergent extension

   Fridtjof Brauns, Nikolas H Claussen ... Boris I Shraiman

   Active and passive contributions to cell shape change and rearrangements can be distinguished from observed cell geometry, revealing the self-organization mechanisms underlying internally-driven epithelial convergent extension.
9. 1. Chromosomes and Gene Expression
   2. Developmental Biology

   N-terminus of Drosophila melanogaster MSL1 is critical for dosage compensation

   Valentin Babosha, Natalia Klimenko ... Oksana Maksimenko

   N‑terminus of MSL1 protein, involved in dosage compensation in Drosophila, is required for the interaction with non-coding roX2 RNA and the assembly of the complex on the male X chromosome.
10. 1. Computational and Systems Biology
    2. Developmental Biology

    Dynamic readout of the Hh gradient in the Drosophila wing disc reveals pattern-specific tradeoffs between robustness and precision

    Rosalío Reyes, Arthur D Lander, Marcos Nahmad

    Theoretical and experimental evidence that Hh signaling dynamics balances robust positioning and sharpness of different target genes in the Drosophila wing disc.