Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Neuroscience

    A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila Ventral Nerve Cord

    Jelly HM Soffers, Erin Beck ... Haluk Lacin
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology

    A-to-I RNA editing of CYP18A1 mediates transgenerational wing dimorphism in aphids

    Bin Zhu, Rui Wei ... Pei Liang
    Binding of miR-3036-5p to CYP18A1 can be prevented by an A-to-I RNA editing, thus elevating CYP18A1 expression, decreasing 20E titer, and finally regulating the wing dimorphism of offspring in aphid.
    1. Developmental Biology

    Neuroprotective role of Hippo signaling by microtubule stability control in Caenorhabditis elegans

    Hanee Lee, Junsu Kang ... Junho Lee
    The Hippo pathway maintains the integrity of differentiated neurons by modulating microtubule stability, and reducing microtubule stability of fully developed neurons offers a potential strategy to delay neuronal aging.
    1. Developmental Biology
    2. Evolutionary Biology

    Molecular dynamics of the matrisome across sea anemone life history

    B Gideon Bergheim, Alison G Cole ... Suat Özbek
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Zinc is a Key Regulator of the Sperm-Specific K+ Channel (Slo3) Function

    Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    • Inadequate
    1. Developmental Biology

    MMP21 behaves as a fluid flow transported morphogen to impart laterality during development

    Tim Ott, Amelie Brugger ... Axel Schweickert
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

    Qian Wang, Hongge Li ... Xin Zhang
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Mutations that prevent phosphorylation of the BMP4 prodomain impair proteolytic maturation of homodimers leading to lethality in mice

    Hyung-seok Kim, Mary L Sanchez ... Jan L Christian
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Developmental Biology

    Knockout of cyclin-dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice

    Alexandra V Bruter, Ekaterina A Varlamova ... Victor V Tatarskiy
    Knockout of CDK8/19, but not its inhibition, impairs spermatogenesis by reducing steroid production in Leydig cells.
    1. Developmental Biology

    A systematic review and embryological perspective of pluripotent stem cell-derived autonomic postganglionic neuron differentiation for human disease modeling

    Thomas A Bos, Elizaveta Polyakova ... Monique RM Jongbloed
    Although methods to efficiently generate functional autonomic postganglionic neurons from human pluripotent stem cells largely mirror signaling cues during embryonic development, several in vivo signaling cues remain to be explored in vitro.

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Albert Cardona
    University of Cambridge, United Kingdom
  3. Kathryn Cheah
    The University of Hong Kong, Hong Kong SAR China
  4. See more editors