Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Visual adaptation in humans revealed that the perception of causality was tuned to the direction of motion while the adaptation transferred across different motion speeds and colors.
Binding of miR-3036-5p to CYP18A1 can be prevented by an A-to-I RNA editing, thus elevating CYP18A1 expression, decreasing 20E titer, and finally regulating the wing dimorphism of offspring in aphid.
The Hippo pathway maintains the integrity of differentiated neurons by modulating microtubule stability, and reducing microtubule stability of fully developed neurons offers a potential strategy to delay neuronal aging.
A novel strategy is described for stimulating a large number of Müller glia to proliferate in mice by manipulating cell cycle components without a damage stimulus.
A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for cholinergic modulation in dopaminergic neuron health.
Kaplan–Meier curves showed that extended adjuvant pyrotinib administered after trastuzumab-based adjuvant therapy provides a promising survival benefit in patients with high-risk HER2-positive breast cancer.
Ljiljana Mihajlovic, Bharat Ravi Iyengar ... Yolanda Schaerli
Experimental evolution of a duplicated gene increases mutational robustness relative to a single-copy gene but does not accelerate phenotypic evolution.
Rab10 deficiency unexpectedly inhibits neuropeptide secretion through two distinct effects on the endoplasmic reticulum (ER), disrupting ER-regulated intracellular Ca²⁺ dynamics and impairing protein synthesis.
