Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Georgia Maria Sagia, Xenia Georgiou ... Sofia Dimou
Unconventional secretion of a plasma membrane purine transporter via Golgi-bypass is established at an early ER-associated secretory compartment revealing that specific cargoes define alternative trafficking routes.
The results of central nervous regulation in mice provide a new neural circuit and receptor regulatory mechanisms for the recovery of consciousness after midazolam administration.
Nrn1, a novel extracellular evolutionarily conserved molecule, impacts cellular electric and metabolic state and contributes to cell fate and immune response outcome.
Clément Mazeaud, Stefan Pfister ... Laurent Chatel-Chaix
Through interactions with viral RNA and NS5, Zika virus changes the composition of the IGF2BP2-containing ribonucleoprotein complex for the benefit of the viral RNA amplification step of its life cycle.
Samyogita Hardikar, Bronte Mckeown ... Jonathan Smallwood
Interactions between attention systems and the default mode network are linked to individual differences in trait and state-level experience and cognition.
A member of the Inhibitor of DNA-binding (Id) gene family, best known as negative regulators of tissue-specific master regulatory bHLH transcription factors, also suppresses non-apoptotic caspase activities.
John P Grogan, Matthias Raemaekers ... Sanjay G Manohar
Muscarinic antagonism is causally involved in motivation and incentivisation in healthy human participants, partially mediated via preparatory neural signatures, with implications for cholinergic treatment of Parkinson's disease.
An analysis of vestibular projection neurons lacking their motor neuron partners resolves outstanding controversies for whether and how motor neurons shape vestibulo-ocular reflex circuit assembly.
A combined approach of genome sequencing and fluctuation assays shows that antibiotic pressure does not induce adaptive mutations in Mycobacterium smegmatis, supporting drug resistance as a consequence of phenotypic tolerance.
Differences in the ribosomal densities of the two daughters produced by a mother Escherichia coli could explain the asymmetry of aging and growth rate in previously reported such daughter pairs.
