Chromosomes and Gene Expression

Latest articles

1. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   A genome-wide nucleosome-resolution map of promoter-centered interactions in human cells corroborates the enhancer-promoter looping model

   Arkadiy K Golov, Alexey A Gavrilov ... Sergey V Razin
2. 1. Chromosomes and Gene Expression

   Chromatin endogenous cleavage provides a global view of yeast RNA polymerase II transcription kinetics

   Jake VanBelzen, Bennet Sakelaris ... Jason H Brickner
3. 1. Chromosomes and Gene Expression
   2. Microbiology and Infectious Disease

   Temporal transcriptional response of Candida glabrata during macrophage infection reveals a multifaceted transcriptional regulator CgXbp1 important for macrophage response and fluconazole resistance

   Maruti Nandan Rai, Qing Lan ... Koon Ho Wong

   The dynamic transcription responses of the human fungal pathogen Candida glabrata during macrophage infection is revealed and a novel transcription factor important for the responses to macrophage, proliferation within macrophage, as well as anti-fungal drug resistance has been discovered.
4. 1. Chromosomes and Gene Expression

   Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain

   Darshika Bohra, Zubairul Islam ... Dimple Notani
5. 1. Chromosomes and Gene Expression
   2. Cancer Biology

   Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

   Ananda Kishore Mukherjee, Subhajit Dutta ... Shantanu Chowdhury
6. 1. Chromosomes and Gene Expression
   2. Neuroscience

   Molecular basis of neurodegeneration in a mouse model of Polr3-related disease

   Robyn D Moir, Emilio Merheb ... Ian M Willis

   A global reduction in tRNA differentially affects brain regions and tissues in a mouse model of Polr3-related disease leading to activation of integrated stress and innate immune responses and neurodegeneration.
7. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions

   Ting-Wen Chen, Hsiao-Wei Liao ... Chung-Te Chang

   For mRNA decapping by enhancing DCP2's mRNA-binding affinity and regulating distinct biological processes through DCP1a and DCP1b, human DCP1 is essential.
8. 1. Cell Biology
   2. Chromosomes and Gene Expression

   The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing crossover formation in C. elegans

   Bhumil Patel, Maryke Grobler ... Needhi Bhalla
9. 1. Chromosomes and Gene Expression
   2. Computational and Systems Biology

   DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

   Yuzhen Liu, Christopher D McGann ... Devin K Schweppe
10. 1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Large-scale analysis of the integration of enhancer-enhancer signals by promoters

    Miguel Martinez-Ara, Federico Comoglio, Bas van Steensel

    A high-throughput enhancer-enhancer-promoter reporter assay indicates that pairs of enhancers generally activate promoters in a near-additive manner, and that promoters transform their collective effect non-linearly.