Browse our latest Chromosomes and Gene Expression articles

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    1. Chromosomes and Gene Expression
    2. Medicine

    LncRNA Snhg3 aggravates hepatic steatosis via PPARγ signaling

    Xianghong Xie, Mingyue Gao ... Xiaojun Liu
    LncRNA-Snhg3 regulates lipid metabolism by affecting chromatin accessibility which indicates that lncRNA-mediated epigenetic modification has a crucial role in the pathology of metabolic dysfunction-associated fatty liver disease.
    1. Chromosomes and Gene Expression

    Nuclear Argonaute protein NRDE-3 switches small RNA binding partners during embryogenesis coincident with the formation of SIMR granules

    Shihui Chen, Carolyn M Phillips
    Not revised
    Reviewed Preprint v1
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

    Zeinab M Chahine, Mohit Gupta ... Karine G Le Roch
    Revised
    Reviewed Preprint v2
    Updated
    1. Chromosomes and Gene Expression

    Prolonged Cell Cycle Arrest in Response to DNA damage in Yeast Requires the Maintenance of DNA Damage Signaling and the Spindle Assembly Checkpoint

    Felix Y Zhou, David P Waterman ... James E Haber
    Revised
    Reviewed Preprint v2
    Updated
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Trans regulation of an odorant binding protein by a proto-Y chromosome affects male courtship in house fly

    Pablo J Delclos, Kiran Adhikari ... Richard Meisel
    An integrative approach is used to identify a mechanism by which the fitness effects of Y chromosomes can manifest via trans effects on autosomal genes, through their effects on male courtship and other sexually selected traits.
    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    HIV integrase compacts viral DNA into biphasic condensates

    Pauline J Kolbeck, Marjolein de Jager ... Willem Vanderlinden
    Not revised
    Reviewed Preprint v1
    1. Chromosomes and Gene Expression

    The Smc5/6 complex counteracts R-loop formation at highly transcribed genes in cooperation with RNase H2

    Shamayita Roy, Hemanta Adhikary ... Damien D'Amours
    1. Chromosomes and Gene Expression

    Heat Shock Factor 1 forms nuclear condensates and restructures the yeast genome before activating target genes

    Linda S Rubio, Suman Mohajan, David S Gross
    In response to ethanol stress, the yeast transcription factor Hsf1 forms nuclear condensates and drives the coalescence of target genes prior to their transcriptional activation while in response to thermal stress these three phenomena are tightly coordinated.
    1. Chromosomes and Gene Expression

    A comparative study of the cryo-EM structures of Saccharomyces cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)

    Ester Vazquez-Fernandez, Jing Yang ... David Barford
    The yeast APC/C cryo-EM structure reveals substantial similarities with the human APC/C structure but also important differences in mechanisms of phosphorylation-dependent regulation and activation by coactivators.
    1. Chromosomes and Gene Expression

    Transcriptional inhibition after irradiation occurs preferentially at highly expressed genes in a manner dependent on cell cycle progression

    Zulong Chen, Xin Wang ... Jessica K Tyler
    Genetic, cellular, and molecular analyses reveal that the reduced abundance of total nascent transcripts that occurs after irradiation is largely due to the repression of histone and rRNA encoding genes.
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