Medicine

Latest articles

1. 1. Medicine

   Pyrotinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (PERSIST): A multicenter phase II trial

   Feilin Cao, Zhaosheng Ma ... Shifen Huang
2. 1. Cell Biology
   2. Medicine

   Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease

   Slaven Crnkovic, Helene Thekkekara Puthenparampil ... Grazyna Kwapiszewska
3. 1. Medicine

   Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis

   Marketa Jirouskova, Karel Harant ... Martin Gregor
4. 1. Medicine

   Time to Eat - A Personalized Circadian Eating Schedule Leads to Weight Loss Without Imposing Calorie Restriction: A Randomized Controlled Pilot Study

   Isabell Wilming, Jana Tuschewski ... Dominic Landgraf
5. 1. Immunology and Inflammation
   2. Medicine

   Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

   Ole Bæk, Tik Muk ... Duc Ninh Nguyen

   Reduced parenteral glucose during neonatal infection redirects hepatic metabolism to oxidative phosphorylation and gluconeogenesis, dampens systemic proinflammatory responses, and significantly enhances survival in preterm newborns.
6. 1. Medicine

   Transplantation of exogenous mitochondria mitigates myocardial dysfunction after cardiac arrest

   Zhen Wang, Jie Zhu ... Xiang Zhou
7. 1. Medicine
   2. Microbiology and Infectious Disease

   Differences in HIV-1 reservoir size, landscape characteristics, and decay dynamics in acute and chronic treated HIV-1 Clade C infection

   Kavidha Reddy, Guinevere Q Lee ... Thumbi Ndung'u

   Extremely early antiretroviral therapy during HIV-1 subtype C infection leads to faster decline in genome-intact viruses, reduced genetic complexity, and immune escape, and may enhance reservoir clearance with additional interventional strategies.
8. 1. Cancer Biology
   2. Medicine

   Development and assessment of a sustainable PhD internship program supporting diverse biomedical career outcomes

   Patrick Brandt, Dawayne Whittington ... Rebekah L Layton

   Internship programs for PhD and postdoctoral trainees are challenging to develop and sustain, but the benefits to interns and other stakeholders are significant and worth the effort and expense.
9. 1. Computational and Systems Biology
   2. Medicine

   Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats

   Hong Yang, Cheng Zhang ... Adil Mardinoglu

   Inhibiting c-Jun N-terminal kinase exerts a cross-tissue therapeutic effect on metabolic dysfunction induced by sucrose overconsumption in rats.
10. 1. Medicine
    2. Stem Cells and Regenerative Medicine

    R-Spondin Mimetic, SZN-043, Induced Proliferation and Wnt Activity, Two Features Deficient in Human Alcohol-Associated Liver Disease

    Trevor Fisher, Mehaben Patel ... Helene Baribault