ME3BP-7 inhibits tumor growth of orthotopically implanted pancreatic cancer cell line Panc 02.13 with high MCT1 expression.
(A) Timeline and design of in vivo tumor experiments. (B) Bioluminescence images of nude mice bearing orthotopic Panc 02.13 tumors. (C) Mean fold change in radiance from day of treatment initiation (** P < 0.01, *** P<0.001 1 way ANOVA. (D) Weights of residual tumors harvested upon termination of therapy (** P < 0.01 Mann-Whitney U test). Created with BioRender.com