Nadine Herzog, Hendrik Hartmann ... Annette Horstmann
Genetic analyses suggest that advantageous genotypes can mitigate the negative effects of high body mass index on cognitive functions involving information updating.
Measuring the activity of hundreds of neurons in macaque brains simultaneously provides further evidence that drift-diffusion dynamics underlie how decisions are made in the brain.
Computational simulations and data analysis show that random clustering in the connections of neurons receiving minimal external cues can generate place fields and their spontaneous activation in trajectory-like sequences.
Sebastián Giunti, María Gabriela Blanco ... Diego Rayes
PTEN mutations disrupt inhibitory GABAergic signaling, causing neurodevelopmental defects that can be mitigated by β-hydroxybutyrate, which activates DAF-16/FOXO and may offer a therapeutic approach for excitation/inhibition imbalances.
Natalie Steinemann, Gabriel M Stine ... Michael N Shadlen
Simultaneous recording from many neurons in macaque lateral intraparietal area reveals the elusive drift-diffusion signal, long suspected to underlie individual perceptual decisions and response times.
Studies of heterogeneity in healthy brain aging reveal varying susceptibilities to aging and delayed development, which deepen aging-development understanding and promote prediction and diagnosis of cognitive decline and neurodegenerative diseases.
