A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
- Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, United Kingdom
- CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Peru
- Universidad Católica Los Ángeles de Chimbote, Instituto de Investigación, Peru
- Facultad de Medicina de la Universidad Nacional de Trujillo, Peru
- Sociedad Científica de Estudiantes de Medicina de la Universidad Nacional de Trujillo-SOCEMUNT, Peru
- Universidad Científica del Sur, Peru
Figures
Figure 1 with 1 supplement
Study selection process.
Figure 1—figure supplement 1
Selection process and number of data sources per year.
In this figure supplement, we show the number of data sources by country and year of data collection.
Figure 2
Trends in mean total cholesterol, LDL-Cholesterol, HDL-Cholesterol and triglycerides in Latin America and the Caribbean.
The solid blue line represents a linear regression trend. Year in the x-axis refers to data collection year. Countries within sub-regions are shown in Supplementary file 1, Table 5. Individual estimates are shown in Supplementary file 1, Table 2.
Figure 3
Trends in prevalence of high total cholesterol, high LDL-Cholesterol, low HDL-Cholesterol and high triglycerides in Latin America and the Caribbean. The solid blue line represents a linear regression trend.
Year in the x-axis refers to data collection year. Countries within sub-regions are shown in Supplementary file 1, Table 5. Studies included in this graphics are those with standard clinically relevant definitions. I.e., total cholesterol ≥150 mg/dl,≥200 mg/dl, or ≥240 mg/dl; LDL-Cholesterol ≥100 mg/dl,≥130 mg/dl, or ≥160 mg/dl; HDL-Cholesterol ≤40 mg/dl in men and ≤50 mg/dl in women; triglycerides ≥ 100 mg/dl,≥130 mg/dl,≥150 mg/dl, or ≥200 mg/dl. That is, prevalence estimates based on other definitions were excluded. Individual estimates are shown in Supplementary file 1, Table 3.
Tables
Table 1
Pooled mean and pooled prevalence estimates since 2005, random-effects meta-analysis.
| Mean (mg/dl) | Lower 95% confidence interval | Upper 95% confidence interval | |
|---|---|---|---|
| Total cholesterol (37 studies) | 193.39 | 189.10 | 197.68 |
| LDL-Cholesterol (30 studies) | 119.98 | 116.08 | 123.88 |
| HDL-Cholesterol (42 studies) | 46.55 | 44.99 | 48.12 |
| Triglycerides (39 studies) | 139.27 | 130.57 | 147.98 |
| Prevalence (%) | Lower 95% confidence interval | Upper 95% confidence interval | |
| High total cholesterol - ≥ 200 mg/dl (six studies) | 34.04 | 19.04 | 49.04 |
| High total cholesterol - ≥ 240 mg/dl (five studies) | 20.97 | 13.51 | 28.43 |
| High LDL-Cholesterol - ≥ 130 mg/dl (two studies) | 40.41 | 29.05 | 51.78 |
| High LDL-Cholesterol - ≥ 160 mg/dl (five studies) | 19.73 | 11.57 | 27.89 |
| Low HDL-Cholesterol ≤ 40(men) and ≤50(women) (nine studies) | 48.27 | 36.31 | 60.22 |
| High Triglycerides ≥ 150 mg/dl (12 studies) | 43.12 | 35.40 | 50.85 |
| High Triglycerides ≥ 200 mg/dl (four studies) | 20.48 | 16.28 | 24.69 |
Additional files
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Supplementary file 1
Word document with checklist for reporting of systematic reviews; search terms used; risk of bias assessment and rationale; table describing the selected studies along with references; table with the mean levels by selected study; table with prevalence estimates by selected study.
- https://cdn.elifesciences.org/articles/57980/elife-57980-supp1-v1.docx
-
Transparent reporting form
- https://cdn.elifesciences.org/articles/57980/elife-57980-transrepform-v1.docx
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A systematic review of population-based studies on lipid profiles in Latin America and the Caribbean
eLife 9:e57980.
https://doi.org/10.7554/eLife.57980
