Zuzana Outla, Gizem Oyman-Eyrilmez ... Martin Gregor
Plectin drives hepatocellular carcinoma progression and metastasis through cytoskeletal reorganization and oncogenic signaling, making it a promising therapeutic target for overcoming therapy resistance.
Prostaglandin E2 inhibits Kv2.2 channels via the EP2/4-PKA signaling pathway, leading to decreased glucose-stimulated action potential firing and insulin secretion in normal pancreatic β-cells.
The discovery of X chromosome-associated protein 5 (Xap5)-mediated transcriptional rewiring of ciliary genes in animals reveals that this regulatory mechanism was conserved during evolution.
Ryan M Finnerty, Daniel J Carulli ... Wipawee Winuthayanon
The oviduct dynamically adapts its molecular makeup over time and space, responding to sperm and embryos by activating inflammatory and metabolic genes in distinct regions to support reproduction.
