Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    MuSK-BMP signaling in adult muscle stem cells maintains quiescence and regulates myofiber size

    Laura A Madigan, Diego Jaime ... Justin R Fallon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids

    Kyoung Jo, Zong-Yuan Liu ... Idse Heemskerk
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Stem Cells and Regenerative Medicine

    Human-induced pluripotent stem cell-derived microglia integrate into mouse retina and recapitulate features of endogenous microglia

    Wenxin Ma, Lian Zhao ... Wei Li
    Transplanted human iPSC-derived microglial cells with immune responses and phagocytic abilities integrate and occupy native microglial cell space and functionally respond to retinal injuries.
    1. Stem Cells and Regenerative Medicine

    Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury

    Tony Marchand, Kemi E Akinnola ... Kira Gritsman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Single Cell Transcriptomics-Informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage

    Angela Papalamprou, Victoria Yu ... Dmitriy Sheyn
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    Cell Death: Caspases promote cell proliferation after necrosis

    Prathibha Yarikipati, Andreas Bergmann
    An enzyme known as caspase, which initiates apoptosis, has a central role in the regeneration of cells and repair of tissue that can occur after necrosis.
    Version of Record
    Insight
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stochastic cell-intrinsic stem cell decisions control colony growth in planarians

    Tamar Frankovits, Prakash Varkey Cherian ... Omri Wurtzel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Stem Cells and Regenerative Medicine

    Notch Signaling: Antibodies get under the skin

    Chiara Levra Levron, Gabriele Piacenti, Giacomo Donati
    By inhibiting receptor-ligand interactions in sebaceous glands, antibodies may be able to treat certain skin conditions.
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    Immune Cells: Growing microglia in the lab

    Jonathan M Levenson, Hio Tong Kam, Dong Feng Chen
    Transplanting microglia derived from human stem cells into mice reveals new possibilities for treating neurodegenerative eye diseases.
    Version of Record
    Insight
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells

    Nathaniel Paul Meyer, Tania Singh ... Diane L Barber
    Clonal naïve human embryonic stem cells assemble an Arp2/3 complex-dependent contractile actin filament ring around colonies that promotes tensional forces favoring cell-cell adhesion and nuclear translocation of YAP to maintain ground-state pluripotency.