Browse our Research Articles

xCas9's ability to recognise diverse DNA sequences stems from structural flexibility in the protospacer adjacent motif (PAM)-interacting cleft and adaptability to PAM-induced conformational changes, paving the way for advanced genome editing tools.

Audiomotor mismatch responses in auditory cortex are amplified by concurrent visuomotor mismatches, highlighting non-hierarchical and multimodal processing of prediction errors.

A panel of serum biomarkers, including dietary and microbial-derived metabolites related to the gut-brain axis, were identified as potential for tracking children at risk of early childhood developmental delays.

IL-6 signaling drives fibroblast activation in tendinopathy, emerging as a promising therapeutic target for these increasingly prevalent and costly tendon conditions.

The combination therapy of colistin, artesunate, and EDTA could serve as a promising approach to combat colistin-resistant Salmonella infections by disrupting bacterial membranes, collapsing proton motive force, and increasing reactive oxygen species levels.

FMT alleviated the intestinal barrier damage caused by enterotoxigenic Escherichia coli infection in antibiotic-induced microbiome-disordered model through increasing the relative abundance of A. muciniphila in the intestine.

The secreted toxin mycolactone has severe effects on the cells lining blood vessels that will play a critical role in the development of swelling in Buruli ulcer disease.

CGRP neurons act as a general alarm system, modulating various defensive behaviors based on magnitude of threat.

A novel method for factorizing complex cellular trajectories into interpretable bifurcation processes enhances the understanding of cell fate determination through the identification of key biological determinants in scRNA-seq data.

Cortical tracking of multi-scale temporal structures supports audiovisual integration of human motion via distinct modes, with superadditive integration at higher-order timescale linked to biological motion processing and autistic traits.