Browse the latest research

Page 21 of 1,757
    1. Medicine

    Pyrotinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (PERSIST): A multicenter phase II trial

    Feilin Cao, Zhaosheng Ma ... Shifen Huang
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Ecology

    Quantifying Feral Pig Interactions to Inform Disease Transmission Networks

    Tatiana Proboste, Abigail Turnlund ... Ricardo J Soares Magalhães
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants

    Balázs István Tóth, Bahar Bazeli ... Thomas Voets
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

    Ulrike Pech, Jasper Janssens ... Patrik Verstreken
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Plant Biology

    Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis

    Maryam Rahmati Ishka, Hayley Sussman ... Magdalena M Julkowska
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Adaptive chunking improves effective working memory capacity in a prefrontal cortex and basal ganglia circuit

    Aneri Soni, Michael J Frank
    This frontostriatal neural network model links the source of working memory capacity limitations to challenges in learning resource management, and mitigates this challenge by learning a 'chunking' strategy.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Secondary structure of the SARS-CoV-2 genome is predictive of nucleotide substitution frequency

    Zach Hensel
    SARS-CoV-2 secondary structure shapes mutation frequencies, constraining viral evolution models predicting fitness can benefit from integrating secondary structure data.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Neuroscience

    An image-computable model of speeded decision-making

    Paul I Jaffe, Gustavo X Santiago-Reyes ... Russell A Poldrack
    Combining biologically-plausible neural network models of vision with traditional decision-making models enables a detailed characterization of how the visual system extracts representations that guide decisions from raw sensory inputs.
    1. Neuroscience

    Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species

    Hans Martin Kjer, Mariam Andersson ... Tim B Dyrby
    Common principles of white matter microstructure and pathway organisation was revealed using diffusion MRI and x-ray synchrotron imaging across resolutions, and employing diffusion tensor, micro-tensor, multi-fiber, and structure tensor models.
    1. Neuroscience

    Volume electron microscopy reveals unique laminar synaptic characteristics in the human entorhinal cortex

    Sergio Plaza-Alonso, Nicolas Cano-Astorga ... Lidia Alonso-Nanclares
    3D electron microscopy provides the first extensive quantitative ultrastructural dataset of synapses of the human entorhinal cortex.