Short Reports

A Short Report allows authors to publish the results of a small number of experiments, provided the conclusion is clear and justified, and the findings are novel and judged to be of high importance.

Latest articles

    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Secondary structure of the SARS-CoV-2 genome is predictive of nucleotide substitution frequency

    Zach Hensel
    SARS-CoV-2 secondary structure shapes mutation frequencies, constraining viral evolution models predicting fitness can benefit from integrating secondary structure data.
    Version of Record
    Short Report
    • Valuable
    • Convincing
    1. Neuroscience

    Characterization of direct Purkinje cell outputs to the brainstem

    Christopher H Chen, Zhiyi Yao ... Wade G Regehr
    Cerebellar Purkinje cells make direct synapses within the parabrachial, vestibular, pontine central gray, and other brainstem nuclei that exhibit spatial gradients and cell specificity consistent with nuanced influences on diverse behaviors.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Cell Biology

    A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)

    Tamás Visnovitz, Dorina Lenzinger ... Edit I Buzas
    A novel 'torn bag mechanism' is described for the release of LC3 positive and negative small extracellular vesicles (exosomes) from amphiectosomes.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Neuroscience

    Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration

    Xing Xiao, Gagik Yeghiazaryan ... Anne Christine Hausen
    Ox1R signaling in dopaminergic neurons regulates context-induced locomotor activity and exploration in mice.
    Version of Record
    Short Report
    • Valuable
    • Solid
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    A new pipeline SPICE identifies novel JUN-IKZF1 composite elements

    Peng Li, Sree Pulugulla ... Warren J Leonard
    Computational pipeline SPICE systematically screens and predicts novel protein-protein binding complexes including the previously unrecognized global association and functional cooperation between IKZF1 and AP1.
    Version of Record
    Short Report
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Medicine

    Complement 3a receptor 1 on macrophages and Kupffer cells is not required for the pathogenesis of metabolic dysfunction-associated steatotic liver disease

    Edwin A Homan, Ankit Gilani ... James C Lo
    Ablation of the G-protein-coupled receptor C3aR1 specifically on macrophages or Kupffer cells does not alter the course of metabolic dysfunction-associated steatotic liver disease in a dietary mouse model.
    1. Neuroscience

    Frequency-specific cortico-subcortical interaction in continuous speaking and listening

    Omid Abbasi, Nadine Steingräber ... Joachim Gross
    Distinct frequency-based interactions between cortical and subcortical regions highlight the cerebellum’s crucial role in speech production and perception.
    Version of Record
    Short Report
    • Valuable
    • Incomplete
    1. Evolutionary Biology

    New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins

    Natalia Jagielska, Thomas G Kaye ... Michael Pittman
    Laser-stimulated fluorescence (LSF) imaging of early pterosaurs uncovers new soft tissue data of tail vane that reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins.
    Version of Record
    Short Report
    • Valuable
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Ciliary length regulation by intraflagellar transport in zebrafish

    Yi Sun, Zhe Chen ... Chengtian Zhao
    The speed of intraflagellar transport, influenced by particle size, shows a positive correlation with ciliary length in zebrafish.
    Version of Record
    Short Report
    • Valuable
    • Solid
    1. Ecology
    2. Microbiology and Infectious Disease

    Novel class IIb microcins show activity against Gram-negative ESKAPE and plant pathogens

    Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
    12 new class IIb microcins have been structurally identified, phylogenetically assessed, and functionally tested for their antimicrobial activity, increasing the total number of these bacteriocins to 17.
    Version of Record
    Short Report
    • Important
    • Solid