Browse our Short Reports

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    1. Evolutionary Biology

    New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins

    Natalia Jagielska, Thomas G Kaye ... Michael Pittman
    Laser-stimulated fluorescence (LSF) imaging of early pterosaurs uncovers new soft tissue data of tail vane that reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins.
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    • Valuable
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Ciliary length regulation by intraflagellar transport in zebrafish

    Yi Sun, Zhe Chen ... Chengtian Zhao
    The speed of intraflagellar transport, influenced by particle size, shows a positive correlation with ciliary length in zebrafish.
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    • Valuable
    • Solid
    1. Ecology
    2. Microbiology and Infectious Disease

    Novel class IIb microcins show activity against Gram-negative ESKAPE and plant pathogens

    Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
    12 new class IIb microcins have been structurally identified, phylogenetically assessed, and functionally tested for their antimicrobial activity, increasing the total number of these bacteriocins to 17.
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    • Important
    • Solid
    1. Neuroscience

    A distributed brain response predicting the facial expression of acute nociceptive pain

    Marie-Eve Picard, Miriam Kunz ... Pierre Rainville
    Facial expression provides a complementary channel to communicate pain experiences and reflects the activation of brain mechanisms partly distinct from those associated with subjective self-reports of pain.
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    • Important
    • Solid
    1. Biochemistry and Chemical Biology

    SLC35G1 is a highly chloride-sensitive transporter responsible for the basolateral membrane transport in intestinal citrate absorption

    Yoshihisa Mimura, Tomoya Yasujima ... Hiroaki Yuasa
    SLC35G1 is the first highly chloride-sensitive transporter localized on the basolateral membrane of intestinal epithelial cells, responsible for citrate absorption.
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    • Important
    • Convincing
    1. Cell Biology

    PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits

    Weihong Xiong, Maozhen Qin, Haining Zhong
    Two alternative models of PKA activation were tested in neurons, and the results support the classical model in which the catalytic subunit dissociated from the regulatory subunit upon activation.
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    • Important
    • Compelling
    1. Cell Biology

    Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms

    Jessica E Schwarz, Antonijo Mrčela ... Amita Sehgal
    Blood-borne factors contribute to changes in the circadian transcriptome with age.
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    • Fundamental
    • Compelling
    1. Cell Biology

    Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

    Ewa K Bomba-Warczak, Karen M Velez ... Francesca E Duncan
    Exceptionally long-lived macromolecules in mammalian ovaries and oocytes serve as pillars for lifelong reproductive health span.
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    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Neuroscience

    Spatial transcriptomics of meningeal inflammation reveals inflammatory gene signatures in adjacent brain parenchyma

    Sachin P Gadani, Saumitra Singh ... Pavan Bhargava
    Leptomeningeal inflammation in a mouse model of multiple sclerosis triggers deeply penetrating gene changes in underlying brain tissue, described using spatial transcriptomics.
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    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics

    TRPML1 gating modulation by allosteric mutations and lipids

    Ninghai Gan, Yan Han ... Youxing Jiang
    Design and characterization of allosteric mutations that recapitulate TRPML1 gating and structural insights into PI(4,5)P2 and sphingomyelin inhibition of TRPML1.
    Version of Record
    Short Report
    • Important
    • Convincing