Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation

    A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome

    Yan Qian, Qiannv Liu ... Pengyan Xia
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation

    Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived stem cell factor

    Chenchen Mao, Yanyu Chen ... Xiangyang Xue
    Resting natural killer cells promote the progress of colon cancer liver metastasis (CCLM), which may be exploited for novel strategies to improve therapeutic outcomes for patients with CCLM.
    1. Immunology and Inflammation

    T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cells

    Josep Garnica, Patricia Solé ... Pere Santamaria
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation
    2. Neuroscience

    Transcriptional responses in a mouse model of silicone wire embolization induced acute retinal artery ischemia and reperfusion

    Yuedan Wang, Ying Li ... Xuan Xiao
    The UPOAO model effectively replicates retinal ischemia in retinal artery occlusion, providing a novel platform for identifying pathogenic genes and advancing therapeutic research.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

    Matthew B McDougal, Anthony M De Maria ... John W Schoggins
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation

    PD-1 negatively regulates helper T cell differentiation into Th2

    Masaki Tajima, Naoko Ikuta ... Akio Ohta
    Not revised
    Reviewed Preprint v1
    1. Cancer Biology
    2. Immunology and Inflammation

    A novel bioinformatics pipeline for the identification of immune inhibitory receptors as potential therapeutic targets

    Akashdip Singh, Alberto Miranda Bedate ... Linde Meyaard
    A bioinformatics pipeline describes 390 putative, novel inhibitory receptors, to facilitate targeted therapeutic strategies for diverse immune cell types in cancer therapy.
    1. Immunology and Inflammation

    LPS-induced systemic inflammation is suppressed by the PDZ motif peptide of ZO-1 via regulation of macrophage M1/M2 polarization

    Hyun-Chae Lee, Sun-Hee Park ... Kyoung Seob Song
    PEGylated PDZ peptide reduces LPS-induced systemic inflammation, restores tissue integrity, decreases pro-inflammatory cytokines, and modulates macrophage populations, showing potential as a therapeutic for systemic inflammation.
    1. Cell Biology
    2. Immunology and Inflammation

    UFMTrack: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices

    Mykhailo Vladymyrov, Luca Marchetti ... Britta Engelhardt
    Revised
    Reviewed Preprint v2
    Updated
    1. Immunology and Inflammation

    A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency

    Yuji Miyatake, Tomokatsu Ikawa ... Ai Kotani
    Not revised
    Reviewed Preprint v1
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