Browse our latest Medicine articles

Page 18 of 59
    1. Medicine

    Biomedical supervisors’ role modeling of open science practices

    Tamarinde L Haven, Susan Abunijela, Nicole Hildebrand
    Supervisors' engagement in open science practices such as data sharing is associated with a greater odds that Ph.D. students engage in these practices and share their data.
    1. Medicine

    Osteoblast-intrinsic defect in glucose metabolism impairs bone formation in type II diabetic male mice

    Fangfang Song, Won Dong Lee ... Fanxin Long
    Osteoblast glucose metabolism is impaired in a mouse model for type II diabetes and can be boosted pharmacologically or genetically to alleviate diabetic osteopenia.
    1. Medicine

    VO2max prediction based on submaximal cardiorespiratory relationships and body composition in male runners and cyclists: a population study

    Szczepan Wiecha, Przemysław Seweryn Kasiak ... Andrzej Klusiewicz
    VO2max in endurance athletes can be accurately predicted by the submaximal cardiopulmonary exercise testing measurements but relying solely on somatic variables allows limited accuracy, which is especially important for physicians and fitness practitioners for proper health and training status monitoring.
    1. Immunology and Inflammation
    2. Medicine

    Transcriptome network analysis implicates CX3CR1-positive type 3 dendritic cells in non-infectious uveitis

    Sanne Hiddingh, Aridaman Pandit ... Jonas JW Kuiper
    CX3CR1-positive dendritic cells are altered in patients with non-infectious uveitis.
    1. Medicine
    2. Neuroscience

    Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer’s disease and neurodegeneration stratified by sex

    Irene Cumplido-Mayoral, Marina García-Prat ... OASIS study
    Brain-Age delta is a non-invasive marker of biological brain aging that is sensitive to the presence of risk factors and altered biomarkers of Alzheimer's disease in non-demented individuals.
    1. Computational and Systems Biology
    2. Medicine

    Local generation and efficient evaluation of numerous drug combinations in a single sample

    Vlad Elgart, Joseph Loscalzo
    Engineered local heterogeneity in drug concentration is used as a tool to encode drug treatment regimens and to predict the macroscopic cellular response to drug perturbations.
    1. Medicine

    The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent

    Karla J Suchacki, Benjamin J Thomas ... William P Cawthorn
    The health benefits of caloric restriction, including decreasing body fat and blood glucose, differ between males and females and this difference depends on the age at which caloric restriction begins.
    1. Medicine
    2. Epidemiology and Global Health

    A systematic assessment of preclinical multilaboratory studies and a comparison to single laboratory studies

    Victoria T Hunniford, Agnes Grudniewicz ... Manoj M Lalu
    Preclinical multilaboratory studies are a robust method to assess promising interventions.
    1. Medicine
    2. Neuroscience

    The need to change: Is there a critical role of midlife adaptation in mental health later in life?

    Friederike Thams, Stefanie Brassen
    A new developmental model of cognitive-emotional adaptation in midlife builds on current findings from lifespan psychology, cognitive neuroscience, and research in late-life depression.
    1. Medicine

    Study of efficacy and longevity of immune response to third and fourth doses of COVID-19 vaccines in patients with cancer: A single arm clinical trial

    Astha Thakkar, Kith Pradhan ... Balazs Halmos
    Third dose of COVID-19 vaccine leads to seroconversion in 56% cancer patients that are seronegative after primary vaccination and a fourth can further boost immune response in patients with hematologic malignancies, which can be predicted by IgM and CD19 levels.