Browse our Research Articles

Page 19 of 1,370
    1. Genetics and Genomics

    Maf-family bZIP transcription factor NRL interacts with RNA-binding proteins and R-loops in retinal photoreceptors

    Ximena Corso Diaz, Xulong Liang ... Anand Swaroop
    Tissue-specific transcription factors, such as basic motif leucine zipper protein NRL, interact with a plethora of RNA-binding proteins to perform pleiotropic functions during distinct steps of transcription process to generate quantitatively precise patterns of gene expression in neuronal cells.
    1. Neuroscience

    Post-ejaculatory inhibition of female sexual drive via heterogeneous neuronal ensembles in the medial preoptic area

    Kentaro K Ishii, Koichi Hashikawa ... Garret D Stuber
    Inhibitory neurons in the female medial preoptic area show persistent activity in response to male ejaculation, and their reactivation is sufficient to suppress female sexual motivation.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Discovering root causal genes with high-throughput perturbations

    Eric V Strobl, Eric Gamazon
    Root causal genes correspond to the initial changes to gene expression that induce a diagnosis and can be reliably detected from bulk RNA-seq after determining a causal ordering from Perturb-seq.
    1. Neuroscience

    Dopamine activity encodes the changing valence of the same stimulus in conditioned taste aversion paradigms

    Maxine K Loh, Samantha J Hurh ... Mitchell F Roitman
    Phasic dopamine cell body activity and release in the nucleus accumbens differentially respond to the taste of sucrose in correlation with its hedonic valuation.
    1. Neuroscience

    Acetylcholine modulates prefrontal outcome coding during threat learning under uncertainty

    Gaqi Tu, Peiying Wen ... Kaori Takehara-Nishiuchi
    Acetylcholine in the prefrontal cortex modulates the impact of surprising outcomes on learning and decision-making.
    1. Stem Cells and Regenerative Medicine

    Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

    Jacob W Klemm, Chloe Van Hazel, Robin E Harris
    A non-apoptotic function of the caspase Dronc is essential to promote tissue repair in response to necrosis via a previously uncharacterized mechanism.
    1. Cell Biology
    2. Plant Biology

    ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability

    Baihong Zhang, Shuqin Huang ... Wenli Chen
    ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4.
    1. Neuroscience

    Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner

    Xin Zhao, Yurim Chae ... Katherine Tschida
    A population of neurons in the hypothalamus promotes social behaviors in female mice following a period of short-term social isolation.
    1. Stem Cells and Regenerative Medicine

    Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

    Shiyu Zhang, Min Zhou ... Wei Zuo
    It is safe to transplant autologous P63+ progenitor cells isolated from healthy bronchi to IPF patients for the treatment of IPF, and preliminary efficacy has been demonstrated in some patients.
    1. Microbiology and Infectious Disease

    Avian-specific Salmonella transition to endemicity is accompanied by localized resistome and mobilome interaction

    Chenghao Jia, Chenghu Huang ... Min Yue
    Newly produced genomic data, as well as available datasets, reveal the pathogen's global transmission history along with the live poultry trade and pinpoint mobile element-driven local Salmonella adaptation.