Browse our Research Articles

Deuterium metabolic imaging quantitatively maps glycolytic and mitochondrial oxidation fluxes in mouse glioblastoma and their association with tumor histopathologic features.

Transmissible tumors in Hydra can manipulate host phenotype by inducing the growth of supernumerary tentacles, enhancing host foraging efficiency and promoting tumor vertical transmission, akin to manipulative parasites.

Attenuation of viral Nef-driven PI3 kinase signaling in B cells precedes the induction of neutralizing antibody responses against a difficult-to-neutralize simian immunodeficiency virus.

Prostaglandin E2 inhibits Kv2.2 channels via the EP2/4-PKA signaling pathway, leading to decreased glucose-stimulated action potential firing and insulin secretion in normal pancreatic β-cells.

Mathematical models of horizontal gene transfer reveal the determinants underlying multistability of microbial communities, offering key insights for the predictive control and engineering of complex microbiota.

A combination of polymer physics theories consistently rationalizes comprehensive experimental effects of salt, ATP, phosphorylation, and sequence charge and arginine/lysine patterns on the reentrant phase behaviors of intrinsically disordered proteins.

Findings challenge the neural noise hypothesis of dyslexia, showing no differences in excitatory/inhibitory balance between individuals with dyslexia and controls.

Computational modeling and in vitro experiments identify a unique conformational state in amyloidogenic light chains, providing a structural basis for amyloidosis and a precise target for drug design.

Common principles of white matter microstructure and pathway organisation was revealed using diffusion MRI and x-ray synchrotron imaging across resolutions, and employing diffusion tensor, micro-tensor, multi-fiber, and structure tensor models.

This frontostriatal neural network model links the source of working memory capacity limitations to challenges in learning resource management, and mitigates this challenge by learning a 'chunking' strategy.