A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation mechanisms.
Hendrik Heinbockel, Gregor Leicht ... Lars Schwabe
Impairing effects of post-retrieval noradrenergic but not glucocorticoid activation on future recall are linked to hippocampal reactivation and category-level reinstatement in ventral temporal cortex during memory retrieval.
The inferior colliculus integrates auditory and cognitive functions, playing critical roles in sensory prediction, reward processing, and decision-making beyond its traditional role as a sensory relay.
Progesterone mediates nongenomic signaling in Xenopus oocyte meiosis by activating a PLA2 activity that requires two membrane receptors ABDH2 and mPRß.
Tgfbr1 signaling governs all processes associated with the trunk to tail transition, including the repositioning of neuro-mesodermal progenitors, as well as the remodeling of the lateral plate mesoderm and embryonic endoderm.
Little Swifts dynamically adjust their foraging behavior to aerial insect abundance, revealing key insights into predator–prey interactions and optimal foraging strategies in aerial environments.
Numerous related sample characteristics affect polygenic score performance, and incorporation of interaction effects increases both model and polygenic score performance.
Geoffrey W Meissner, Allison Vannan ... FlyLight Project Team
Thousands of cell-type-specific split-GAL4 driver lines and a massive, searchable image collection enable Drosophila neuroscientists to target neurons of interest with increased precision.
In feedforward networks with random connectivity, connection motifs underlying the detection of short clusters and activity sequences are likely to converge on a subset of postsynaptic neurons purely by chance.
Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
