Browse our Research Articles

Page 32 of 1,372
    1. Neuroscience

    Supralinear dendritic integration in murine dendrite-targeting interneurons

    Simonas Griesius, Amy Richardson, Dimitri Michael Kullmann
    NMDA receptors mediate prominent supralinear summation of clustered excitatory inputs to the dendrites of neurogliaform and oriens-lacunosum moleculare interneurons of the hippocampus, showing that these cells perform sub-cellular computations.
    1. Immunology and Inflammation

    Role of hepatocyte RIPK1 in maintaining liver homeostasis during metabolic challenges

    Weigao Zhang, Hu Liu ... Dan Weng
    Hepatocyte RIPK1 plays an important role in liver physiology, preventing liver injury and inflammation during metabolic stresses like acute fasting.
    1. Neuroscience

    Multimodal neural correlates of childhood psychopathology

    Jessica Royer, Valeria Kebets ... Boris C Bernhardt
    A multivariate approach identifying structural and functional factors underpinning dimensions of psychopathology in over 5000 children.
    1. Medicine
    2. Neuroscience

    Cold induces brain region-selective cell activity-dependent lipid metabolism

    Hyeonyoung Min, Yale Y Yang, Yunlei Yang
    It is of significance in identifying temperature sensitive brain regions in brain energy metabolism, as which might provide potential targetable sites in the treatment of brain lipid metabolism-associated neurological disorders.
    1. Neuroscience

    Glia control experience-dependent plasticity in an olfactory critical period

    Hans C Leier, Alexander J Foden ... Heather T Broihier
    A Drosophila olfactory circuit exhibits experience-dependent glial pruning during a well-defined critical period, with long-term consequences for odor processing.
    1. Neuroscience

    Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons

    Shun Hiramatsu, Kokoro Saito ... Hiromu Tanimoto
    The opposing dopamine receptors Dop1R1 and Dop2R are both enriched around the pre- and postsynaptic sites of different types of neurons, including dopaminergic neurons, in the fly brain.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

    Ana Patrícia Graça, Vadim Nikitushkin ... Gerald Lackner
    The mftG gene, present in the majority of mycofactocin gene clusters, encodes an oxidoreductase that facilitates ethanol utilization by reoxidation of mycofactocins and channeling electrons towards the respiratory chain.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    eIF3 engages with 3’-UTR termini of highly translated mRNAs

    Santi Mestre-Fos, Lucas Ferguson ... Jamie HD Cate
    The extent of human eukaryotic translation initiation factor eIF3 interaction with the 3' ends of mRNA 3' untranslated regions (3'-UTRs) correlates with the level of translation.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: A genomic epidemiology study

    Gillian AM Tarr, Linda Chui ... Tim A McAllister
    E. coli O157 infections in humans are closely linked to strains circulating in local cattle populations, with some strains persisting as long as 13 years.
    1. Neuroscience

    Nutritional state-dependent modulation of insulin-producing cells in Drosophila

    Rituja S Bisen, Fathima Mukthar Iqbal ... Jan M Ache
    An in vivo electrophysiology approach identifies an incretin-like effect in Drosophila insulin-producing cells, highlighting key circuit dynamics which govern glucose homeostasis via conserved mechanisms.