Browse our latest Genetics and Genomics articles

Unveiling the high-confidence protein–protein interaction networks of human and fly α-arrestins provides insights into conserved and species-specific functional roles depending on their protein domains and motifs.

Eliminating eukaryotic initiation factor 2 (eIF2) from wild-type budding yeast had little impact on translation of individual mRNAs, including those with regulatory upstream open-reading frames, even when canonical initiation factor eIF2 activity was impaired.

Spatially-resolved transcriptomics and single-nucleus RNA-sequencing are applied to the human locus coeruleus to characterize the gene expression profiles of norepinephrine (NE) neurons and other cell populations in this critical brain region, with all data made publicly available.

CRISPR knock-outs and functional genomic approaches probe the regulatory mechanism restricting the Hox gene Ubx to butterfly hindwings, explaining color pattern differentiation from forewings.

Adult Drosophila exposed to auxin at the recommended concentrations for the AGES transgene expression system display defects in feeding behavior, have altered metabolic transcripts, and have reduced triacylglyceride levels.

Arabidopsis lines were screened for resistance to TuMV, identifying a region on chromosome 2 linked to necrosis that includes an antiviral gene.

Mice lacking Tmem263 are dwarfs, and this phenotype is associated with reduced hepatic growth hormone (GH) receptor expression, a deficit in GH-induced signaling, and low insulin-like growth factor 1 level.

A population resource to investigate mechanisms of organ communication.

Results from the largest tuberculosis genome-wide association study meta-analysis identified a significant association in the human leukocyte antigen class II region, rs28383206, across multiple populations.