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The novel role of Adgrf1 in the progression of fatty liver was revealed and targeting Adgrf1 is a promising therapeutic strategy for treating NAFLD patients.

The expansion of our understanding about the regulation of iron metabolism, erythropoiesis, and the crosstalk between them has enabled delineating the pathophysiology of multiple diseases and provided rationale for novel therapeutic interventions.

Decline in cervical cancer screening and challenges faced by healthcare professionals and patients when the pandemic was declared emphasize the importance of implementing human papillomavirus (HPV) primary screening, HPV self-sampling, and telemedicine to continue cervical cancer screening and care.

Melanocortin 1 receptor (MC1-R) deficiency in hepatocytes increases cholesterol levels in the circulation and liver in mice, while selective activation of MC1-R reduces cellular cholesterol content in cultured hepatocytes.

MS-Hu6 biotherapeutic formulation for the treatment of osteoporosis, obesity, and Alzheimer's disease.

Definitions of reproducibility vary considerably across disciplines and overall rates of reproducibility are low irrespective of the definition used.

A laboratory experiment provides the first evidence that framing a sham treatment as personalised to one's genetics and physiology increases its placebo effect on pain.

Enhancing the management of Gaucher disease patients through multidimensional risk assessment serves as a roadmap towards personalized medicine in the context of a rare disease.

The sialylation of RANK⁺TLR2⁺ monocytes contributes to osteoclastogenesis and bone destruction in rheumatoid arthritis.