Browse our latest Stem Cells and Regenerative Medicine articles

A small molecule compound Dwn1, identified through high-throughput screening using Npas2 as the molecular target, enhances wound healing in a murine incisional wound model.

iMyoblasts, a novel iPS-derived PAX3 muscle stem cell for gene editing, muscle engraftment, and stem cell therapeutics to treat muscle injury and muscular dystrophies.

Amino acid and sugar supplement induce appendage/limb regeneration in cnidarians, insects, and mammals.

Signaling from the limb nerves regulates the rate of growth and the overall size of the regenerating limb.

Regrowing new body parts requires neural input to restore appropriately sized limbs in salamanders.

In vivo modulation of the prostaglandin, interferon, or granulocyte colony-stimulating factor pathway induces rapid and specific transcriptional changes in hematopoietic stem cells with significant heterogeneity in the cellular response.

Novel human iPS cell derived and primary skeletal muscle stem cells show that abnormal ACVR1 activation increases osteogenic/ECM gene expression and impairs myofiber repair, while revealing muscle-specific regenerative properties.

Human pluripotent stem cell modeling of the ATOH1 lineage identifies a temporal shift in the expression of key transcriptional regulators in the developing human cerebellum, this molecular divergence may drive the protracted development of the human cerebellum compared to rodents.

Oon and Prehoda discover cortical actomyosin dynamics that polarize asymmetrically dividing neural stem cells.

The IRE1/XBP1 signaling in myofibers is essential for robust skeletal muscle regeneration in response to injury.