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Fitting a mechanistic model to data from SARS-CoV-2 source-recipient pairs generates improved estimates of changes in infectiousness during infection, indicating substantial transmission shortly before symptom onset.

Patients exposed to ⍺1-AR antagonists have reduced risks of mechanical ventilation and death in lower respiratory tract infection-related illnesses, highlighting the need for prospective trials assessing ⍺1-AR antagonists' effectiveness in COVID-19.

Combined evidence of human genetics, in vitro cardiomyocyte differentiation, and mouse model indicates that SORBS2 is a regulator of second heart field development and its deficiency causes seemingly opposite atrial septal defects.

The subcellular activity of presynaptic terminals of dopamine neurons shapes the reward magnitude and memory specificity.

Distinct dorsal periaqueductal gray ensembles encode threat approach and avoidance behavioral states.

Widespread asymptomatic SARS-CoV2 infection affected nearly 100 million Indians by September 2020 with a subsequent decline in new cases, which may be attributable to increased population immunity, albeit seeing reduced neutralization activity at 6 months this respite may be temporary.

Adult stem cells acquire increased DNA damage as they migrate to a wound site and require active DNA repair mechanisms for normal migration.

Monogamous rodents of the genus Peromyscus, upon disruption of pair bonds, acquire increased oncogenic activity.

Overgrowth of the yeast Pichia kudriavzevii within the neonatal gut microbiota increases allergic airway disease severity later in life and may be inhibited by short-chain fatty acids.

Spontaneous and evoked patterns of neural activity in the larval zebrafish tectum become less similar over development, in contrast with a previous hypothesis for the computational role of spontaneous activity.