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Microfluidic culture and high-resolution 3-D microscopy establish that bacteriophages trapped in the outer matrix layers of a bacterial biofilm remain active and can prevent colonization of the biofilm by newly arriving bacteria.

The fast spreading of neural activity across the brain has a complex structure, imposed by the white-matter bundles.

Genetic sequencing has led to the increased diagnoses of rare diseases, strategies such as repurposing drugs and global metabolomics offer promise and bring hope to afflicted families.

Several previously proposed cell-surface receptors for hantaviruses could be deleted in endothelial cells with little or no effect on infection, indicating that critical hantavirus entry factors remain undiscovered.

Cerebellar degeneration disrupts the use of interval-based temporal cues, but not rhythmic cues, to proactively modulate perceptual sensitivity, implicating the cerebellum in temporal control of visual attention.

The size of a subcellular structure, yeast actin cables, scales with the linear dimensions of the cell, which is achieved by feedback control of their growth rate.

The transcription factor Snai1b maintains the myocardial wall integrity by limiting cell extrusions and regulating the intermediate filament gene desmin b.

The key mechanism for opioid-like biased agonists to provide analgesia but not respiratory depression does not involve ß-arrestin 2.

The T12 Vibrio cholerae lineage has been continuously circulating in West Africa since at least 2012, highlighting the importance of regional disease control efforts.

Finding that circulating Z alpha-1 antitrypsin polymers, a feature of ZZ AAT deficiency, lower the expression of CX3CR1 on peripheral blood mononuclear cells encourages more detailed analyses on different circulating misfolded proteins and their role on immune cell surveillance/function.