Browse our Short Reports

Page 19 of 60
    1. Developmental Biology

    Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion

    Naokazu Inoue, Yoshihisa Hagihara, Ikuo Wada
    Mammalian fertilization is accomplished through integrating various molecular pathways that include evolutionarily conserved factors, DCST1 and DCST2.
    1. Neuroscience

    Selective dendritic localization of mRNA in Drosophila mushroom body output neurons

    Jessica Mitchell, Carlas S Smith ... Scott Waddell
    Specific mRNAs localize to the dendrites of Drosophila mushroom body output neurons.
    1. Genetics and Genomics
    2. Medicine

    Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study

    Chiara Fallerini, Sergio Daga ... Elisa Frullanti
    In the context of susceptibility to severe COVID-19, the observations of a study provide the basis for a personalized interferon-based therapy in patients with rare TLR7 variants.
    1. Neuroscience

    Locus coeruleus spiking differently correlates with S1 cortex activity and pupil diameter in a tactile detection task

    Hongdian Yang, Bilal A Bari ... Daniel H O'Connor
    Correlations among LC spiking, membrane potential in S1 cortex, and pupil diameter vary within individual trials of a tactile detection task.
    1. Immunology and Inflammation

    Opposing effects of T cell receptor signal strength on CD4 T cells responding to acute versus chronic viral infection

    Marco Künzli, Peter Reuther ... Carolyn G King
    T cell receptor signal strength correlates positively with Th1 generation during acute infection but negatively during chronic infection.
    1. Cancer Biology

    Dissecting phenotypic transitions in metastatic disease via photoconversion-based isolation

    Yogev Sela, Jinyang Li ... Ben Z Stanger
    A photoconversion-based isolation technique enables systematic investigation of spatially distinct small metastases (microcolonies) versus large lesions (macrometastases).
    1. Neuroscience

    α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels

    Reeba Susan Jacob, Cédric Eichmann ... Philipp Selenko
    Plasma membrane clusters of the Parkinson's disease protein α-synuclein colocalize with negatively charged phospholipids involved in endocytosis and exocytosis.
    1. Evolutionary Biology

    Preliminary paleohistological observations of the StW 573 (‘Little Foot’) skull

    Amélie Beaudet, Robert C Atwood ... Dominic Stratford
    Virtual investigation of the 3.67-million-year-old skull of 'Little Foot' using synchrotron radiation reveals histological details of Australopithecus dental and bone tissues.
    1. Neuroscience

    Control of feeding by Piezo-mediated gut mechanosensation in Drosophila

    Soohong Min, Yangkyun Oh ... Stephen Liberles
    Gut-innervating sensory neurons detect large food volumes and inhibit feeding in Drosophila through the mechanically gated ion channel Piezo.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation

    Pengfei Xu, Haoze V Yu ... J Gage Crump
    Foxc1 proteins prepare the genomes of neural crest-derived cells to facilitate their later development into the cartilages that support the embryonic face.