In the context of susceptibility to severe COVID-19, the observations of a study provide the basis for a personalized interferon-based therapy in patients with rare TLR7 variants.
A photoconversion-based isolation technique enables systematic investigation of spatially distinct small metastases (microcolonies) versus large lesions (macrometastases).
Reeba Susan Jacob, Cédric Eichmann ... Philipp Selenko
Plasma membrane clusters of the Parkinson's disease protein α-synuclein colocalize with negatively charged phospholipids involved in endocytosis and exocytosis.
Amélie Beaudet, Robert C Atwood ... Dominic Stratford
Virtual investigation of the 3.67-million-year-old skull of 'Little Foot' using synchrotron radiation reveals histological details of Australopithecus dental and bone tissues.
Foxc1 proteins prepare the genomes of neural crest-derived cells to facilitate their later development into the cartilages that support the embryonic face.