Single-cell RNA sequencing of biopsy samples from advanced-stage lung cancer reveals tumor and immune cell features associated with response to immune checkpoint therapy.
FABP4 plays a central role in driving the formation lipid-laden macrophages induced by unsaturated fats and enhances macrophage-tumor interactions, thereby promoting breast cancer migration and metastasis.
Rebecca Warfvinge, Linda Geironson Ulfsson ... Göran Karlsson
Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.
A new approach helps examine the proportion of cancerous and healthy stem cells in patients with chronic myeloid leukemia and how this influences treatment outcomes.
