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    1. Cell Biology
    2. Neuroscience

    Projection neurons are necessary for the maintenance of the mouse olfactory circuit

    Luis Sánchez-Guardado, Peyman Razavi ... Carlos Lois
    Ablation of olfactory projection neurons in adult mice triggers sprouting of the apical dendrite of remaining neurons towards multiple nearby glomeruli and disrupts the odor map.
    1. Cell Biology
    2. Neuroscience

    GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes

    Dhanesh Sivadasan Bindu, Justin T Savage ... Cagla Eroglu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Control of cell retraction and protrusion with a single protein

    Jean De Seze, Maud Bongaerts ... Mathieu Coppey
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    • Convincing
    1. Cell Biology
    2. Genetics and Genomics

    Kinesin Autoinhibition Requires Elbow Phosphorylation

    Guanghan Chen, Zhengyang Guo ... Guangshuo Ou
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins

    Satoshi Ninagawa, Masaki Matsuo ... Kazutoshi Mori
    The fate of glycoproteins in the endoplasmic reticulum whether they are directed toward folding or targeted to degradation depends on a tug of war between UGGT1 and EDEM family proteins.
    1. Cell Biology
    2. Developmental Biology

    Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

    Qian Wang, Hongge Li ... Xin Zhang
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Cell Biology

    Calcium tunneling through the ER and transfer to other organelles for optimal signaling in Toxoplasma gondii

    Zhu-Hong Li, Beejan Asady ... Silvia NJ Moreno
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/β-catenin signaling

    Senem Ntourmas, Martin Sachs ... Dominic B Bernkopf
    Biochemical detection of endogenous, paralog-specific DVL2 complexes, molecular characterization of underlying protein domains and functional evidence for their importance extend the knowledge of Wnt pathway regulation through DVL2 biomolecular condensates.
    1. Cell Biology
    2. Neuroscience

    Endogenous hydrogen peroxide positively regulates secretion of a gut-derived peptide in neuroendocrine potentiation of the oxidative stress response in Caenorhabditis elegans

    Qi Jia, Drew Young ... Derek Sieburth
    Stress-regulated secretion of an intestinal peptide positively regulates the antioxidant response by promoting neuropeptide release from the nervous system, defining a gut-to-brain-to-gut endocrine axis in the oxidative stress response.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A conserved cell-pole determinant organizes proper polar flagellum formation

    Erick E Arroyo-Pérez, John C Hook ... Simon Ringgaard
    FipA is a novel component required for bacteria that rely on FlhF/FlhG to properly localize their flagella to the cell pole.
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