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    1. Cell Biology
    2. Chromosomes and Gene Expression

    The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing crossover formation in C. elegans

    Bhumil Patel, Maryke Grobler ... Needhi Bhalla
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Computational and Systems Biology

    De novo-designed minibinders expand the synthetic biology sensing repertoire

    Zara Y Weinberg, Sarah S Soliman ... Hana El-Samad
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Cell Biology

    Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome

    Laura Childers, Esther Park ... Michel Bagnat
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion

    Lu Yang, Zijin Lin ... Li Liu
    The established triple co-culture blood-–brain barrier (BBB) model could be used for predicting drugs’ BBB permeability, and co-culture with neurons and astrocytes enhanced brain endothelial cells’ integrity by secreting GDNF, which upregulated claudin-5 and VE-cadherin expression.
    1. Cell Biology
    2. Neuroscience

    Rab11 suppresses neuronal stress signaling by localizing dual leucine zipper kinase to axon terminals for protein turnover

    Seung Mi Kim, Yaw Quagraine ... Jung Hwan Kim
    Coupling between subcellular localization and protein turnover of a neuronal stress kinase, DLK, and its role in neuronal stress responses in Drosophila.
    1. Cell Biology

    Image Correlation Spectroscopy is a Robust Tool to Quantify Cellular DNA Damage Response

    Angelica A Gopal, Bianca Fernandez ... J Matthew Dubach
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Arp2/3 complex activity enables nuclear YAP for naïve pluripotency of human embryonic stem cells

    Nathaniel Paul Meyer, Tania Singh ... Diane L Barber
    Clonal naïve human embryonic stem cells assemble an Arp2/3 complex-dependent contractile actin filament ring around colonies that promotes tensional forces favoring cell-cell adhesion and nuclear translocation of YAP to maintain ground-state pluripotency.
    1. Cell Biology

    Time-resolved proximity proteomics uncovers a membrane tension-sensitive caveolin-1 interactome at the rear of migrating cells

    Eleanor Martin, Rossana Girardello ... Alexander Ludwig
    Membrane tension controls the dynamic assembly and disassembly of caveolae and their association with the F-actin cortex in migrating cells.
    1. Cell Biology
    2. Developmental Biology

    Limited column formation in the embryonic growth plate implies divergent growth mechanisms during pre- and postnatal bone development

    Sarah Rubin, Ankit Agrawal ... Elazar Zelzer
    Modulation of division plane rotation in proliferating chondrocytes determines the ratio of clusters and columns, which may support the multifunctional design of the growth plate.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Stem Cells: Don’t be so naïve

    Valerie Horsley, Aya Nassereddine
    New evidence sheds light on actin regulation of pluripotency in human embryonic stem cells.
    Version of Record
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