Browse our latest Cell Biology articles

Page 14 of 310
    1. Cell Biology
    2. Plant Biology

    Autophagosome development and chloroplast segmentation occur synchronously for piecemeal degradation of chloroplasts

    Masanori Izumi, Sakuya Nakamura ... Shinya Hagihara
    A plant autophagy pathway transports chloroplast stroma and envelope components into the vacuole through the division and encapsulation of the site of chloroplasts that is associated with developing autophagosome.
    1. Cell Biology

    Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistance

    Jeongsik Kim, Dahyun Kim ... Dae-Sik Lim
    Formation of a giant unilocular vacuole through a macropinocytosis-like process in cells with disrupted actin cytoskeleton promotes resistance to anoikis.
    1. Cell Biology

    PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits

    Weihong Xiong, Maozhen Qin, Haining Zhong
    Two alternative models of PKA activation were tested in neurons, and the results support the classical model in which the catalytic subunit dissociated from the regulatory subunit upon activation.
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    Short Report
    • Important
    • Compelling
    1. Cell Biology

    SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus

    Dandan Wu, Chi Yang ... Zhenhong Zhuang
    Chromatin immunoprecipitation sequencing and RNA sequencing have elucidated the complex transcript regulation pathways orchestrated by SntB, pivotal for Aspergillus flavus's development, mycotoxin production, and virulence.
    1. Cell Biology

    Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2

    Guangyan Yang, Jiaqing Xiang ... Shu Yang
    SIRT4 regulates cellular communication network factor 2 expression through U2 small nuclear RNA auxiliary factor 2-mediated pre-mRNA splicing, presenting a potential therapeutic target for kidney fibrosis.
    1. Cell Biology
    2. Genetics and Genomics

    Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling

    Priyanka Das, Alejandro Aballay, Jogender Singh
    Calcineurin inhibition has opposing effects on Caenorhabditis elegans lifespan and survival on pathogens via its role in the defecation motor program.
    1. Cell Biology

    Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms

    Jessica E Schwarz, Antonijo Mrčela ... Amita Sehgal
    Blood-borne factors contribute to changes in the circadian transcriptome with age.
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    Short Report
    • Fundamental
    • Compelling
    1. Cell Biology

    Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

    Ewa K Bomba-Warczak, Karen M Velez ... Francesca E Duncan
    Exceptionally long-lived macromolecules in mammalian ovaries and oocytes serve as pillars for lifelong reproductive health span.
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    Short Report
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Hundreds of myosin 10s are pushed to the tips of filopodia and could cause traffic jams on actin

    Julia Shangguan, Ronald S Rock
    Improved technology for counting proteins captures myosin 10 dynamics throughout the filopodial lifecycle, defines requirements for initiating filopodia, and reveals a crowded filopodial tip where motors frequently exceed available actin.
    1. Cancer Biology
    2. Cell Biology

    Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

    Francesca Butera, Julia E Sero ... Chris Bakal
    A live imaging and computational approach reveals feedback loops involving F-actin dynamics that regulate the NF-κB transcription factor RELA.