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Page 18 of 310
    1. Cell Biology
    2. Neuroscience

    Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency

    Apostolos Papandreou, Nivedita Singh ... Robin Ketteler
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins

    Kristina Ehring, Sophia Friederike Ehlers ... Kay Grobe
    A composite hedgehog release model that incorporates and supports a previously disparate set of observations has been presented.
    1. Cell Biology
    2. Immunology and Inflammation

    Arpin deficiency increases actomyosin contractility and vascular permeability

    Armando Montoya-Garcia, Idaira M Guerrero-Fonseca ... Michael Schnoor
    Arpin regulates actomyosin contractility and endothelial barrier integrity by controlling the activity of the kinases ROCK1 and ZIPK, but not Arp2/3.
    1. Cell Biology

    WNKs regulate mouse behavior and alter central nervous system glucose uptake and insulin signaling

    Ankita B Jaykumar, Derk Binns ... Melanie H Cobb
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Reactive oxygen species suppress phagocyte surveillance by oxidizing cytoskeletal regulators

    Iuliia Ferling, Steffen Pfalzgraf ... Spencer A Freeman
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells

    Affiong I Oqua, Kin Chao ... Alejandra Tomas
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Point of View: Teaching troubleshooting skills to graduate students

    Gina Partipilo, Yang Gao ... Benjamin K Keitz
    Pipettes and Problem Solving is an initiative that teaches some of the skills needed to figure out why an experiment is producing unexpected results.
    1. Cell Biology

    Kidney Fibrosis: Lock out SIRT4

    Kaiqiang Zhao, Zhongjun Zhou
    The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
    Version of Record
    Insight
    1. Cell Biology
    2. Neuroscience

    CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function

    Longxin Xie, Jessica Merjane ... Christopher J Donnelly
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi

    Daniel M Williams, Andrew A Peden
    Recruitment of NLRP3 to the Golgi is controlled by the reversible addition of a lipid anchor adjacent to the polybasic region.
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