Browse our latest Genetics and Genomics articles

Page 4 of 141
    1. Genetics and Genomics

    Beyond A and B Compartments: how major nuclear locales define nuclear genome organization and function

    Omid Gholamalamdari, Tom van Schaik ... Andrew S Belmont
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Genetics and Genomics

    IDH1 regulates human erythropoiesis by eliciting chromatin state reprogramming

    Mengjia Li, Hengchao Zhang ... Lixiang Chen
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Loss of CTRP10 results in female obesity with preserved metabolic health

    Fangluo Chen, Dylan C Sarver ... G William Wong
    Mice lacking the secreted hormone, CTRP10, represent a unique female model of obesity with preserved metabolic health, highlighting sex-specific mechanisms that uncouple obesity from metabolic dysfunction.
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    A multiomic study reveals the role of ZFHX3 transcription factor in daily timekeeping with a combination of transcription factor and histone ChIP-seq and time-resolved RNA-seq in the mammalian central clock.
    1. Genetics and Genomics

    MerQuaCo: a computational tool for quality control in image-based spatial transcriptomics

    Naomi Martin, Paul Olsen ... Jack Waters
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Exceptional
    1. Evolutionary Biology
    2. Genetics and Genomics

    The genomic legacy of aurochs hybridisation in ancient and modern Iberian cattle

    Torsten Günther, Jacob Chisausky ... Cristina Valdiosera
    After their introduction to the Iberian peninsula, domestic cattle hybridised with mostly male wild aurochs for millennia until human actions likely ended this process about 4000 years ago.
    1. Cell Biology
    2. Genetics and Genomics

    Cytosolic Carboxypeptidase 5 maintains mammalian ependymal multicilia to ensure proper homeostasis and functions of the brain

    Rubina Dad, Yujuan Wang ... Hui-Yuan Wu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics

    Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle

    Daigo Miyazaki, Mitsuto Sato ... Akinori Nakamura
    BMD mice with three different in-frame deletions corresponded to the severity of BMD patients with the same deletions, and they showed type IIa muscle fibers reduction with morphological capillary changes.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice

    Chong Chen, Qian Liu ... Xinting Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete