Mice lacking the secreted hormone, CTRP10, represent a unique female model of obesity with preserved metabolic health, highlighting sex-specific mechanisms that uncouple obesity from metabolic dysfunction.
A multiomic study reveals the role of ZFHX3 transcription factor in daily timekeeping with a combination of transcription factor and histone ChIP-seq and time-resolved RNA-seq in the mammalian central clock.
Torsten Günther, Jacob Chisausky ... Cristina Valdiosera
After their introduction to the Iberian peninsula, domestic cattle hybridised with mostly male wild aurochs for millennia until human actions likely ended this process about 4000 years ago.
BMD mice with three different in-frame deletions corresponded to the severity of BMD patients with the same deletions, and they showed type IIa muscle fibers reduction with morphological capillary changes.