Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation

    RAG1 and RAG2 non-core regions are implicated in leukemogenesis and off-target V(D)J recombination in BCR-ABL1-driven B-cell lineage lymphoblastic leukemia

    Xiaozhuo Yu, Wen Zhou ... Yanhong Ji
    Non-core RAG regions, especially RAG1, maintain V(D)J recombination accuracy and genomic stability, reducing malignant characteristics and off-target recombination in BCR-ABL1+ B-cell acute lymphoblastic leukemia.
    1. Immunology and Inflammation

    PIM kinase control of CD8 T cell protein synthesis and cell trafficking

    Julia M Marchingo, Laura Spinelli ... Doreen A Cantrell
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation
    2. Cancer Biology

    Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers

    Sofia V Krasik, Ekaterina A Bryushkova ... Ekaterina O Serebrovskaya
    Revised
    Reviewed Preprint v2
    Updated
    1. Cell Biology
    2. Immunology and Inflammation

    Stimulation-induced cytokine polyfunctionality as a dynamic concept

    Kevin Portmann, Aline Linder, Klaus Eyer
    Resolving parallel and concurrent cytokine secretion is essential to studying polyfunctional cytokine-secreting cells, and to differentiating immune response granularity from unwinding the complexity and heterogeneity of cytokine responses.
    1. Immunology and Inflammation
    2. Medicine

    Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial

    Joanna C Porter, Jamie Inshaw ... Venizelos Papayannopoulos
    Nebulized dornase alfa endonuclease reduces inflammation, coagulopathy, and the length of hospitalization in individuals with severe COVID-19 pneumonia.