Browse our latest Immunology and Inflammation articles

Page 10 of 110
    1. Immunology and Inflammation

    A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis

    Jyotsna, Binayak Sarkar ... Rajesh S Gokhale
    Studies in murine model identify hepatic Rela-Stat3 network as a potential driver of gut inflammation and a novel therapeutic target for inflammatory bowel disease, offering new insights into liver-gut crosstalk.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Vaccines: How do adjuvants enhance immune responses?

    Rekha R Rapaka
    By altering which peptide antigens are presented to CD4+ T cells, adjuvants affect the specificity of the immune response.
    Version of Record
    Insight
    1. Immunology and Inflammation

    Prdm1 positively regulates liver Group 1 ILCs cancer immune surveillance and preserves functional heterogeneity

    Jitian He, Le Gao ... Youwei Wang
    Prdm1 (BLIMP1) promotes liver Group 1 ILCs cancer surveillance and preserves functional heterogeneity.
    1. Immunology and Inflammation

    Endocannabinoids and their receptors modulate endometriosis pathogenesis and immune response

    Harshavardhan Lingegowda, Katherine B Zutautas ... Chandrakant Tayade
    Cannabinoid receptors CNR1 and CNR2 play distinct roles in endometriosis pathogenesis, potentially contributing to disease initiation and progression through differential modulation of T cell function and the lesion microenvironment.
    1. Immunology and Inflammation

    SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

    Somen K Mistri, Brianna M Hilton ... Jonathan E Boyson
    Revised
    Reviewed Preprint v2
    Updated
    1. Medicine
    2. Immunology and Inflammation

    JAK inhibition decreases the autoimmune burden in Down syndrome

    Angela L Rachubinski, Elizabeth Wallace ... Joaquin M Espinosa
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation
    2. Neuroscience

    Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice

    Nicolas Aubert, Madeleine Purcarea ... Gilles Marodon
    Regulatory T cells produce analgesic opioid peptides that limit heat sensitivity in mice, revealing a novel pain regulation mechanism independent of inflammation control.
    1. Immunology and Inflammation

    MicroRNA-26b protects against MASH development and can be efficiently targeted with lipid nanoparticles

    Linsey JF Peters, Leonida Rakateli ... Emiel PC van der Vorst
    Not revised
    Reviewed Preprint v1
    1. Immunology and Inflammation

    Amphibian mast cells serve as barriers to chytrid fungus infections

    Kelsey A Hauser, Christina N Garvey ... Leon Grayfer
    Enriching amphibian, Xenopus laevis, cutaneous mast cells confers protection against Batrachochytrium dendrobatidis chytrid fungus infections.
    1. Immunology and Inflammation

    Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice

    Andrea Vecchione, Mohsen Khosravi-Maharlooei ... Megan Sykes
    Not revised
    Reviewed Preprint v1