Browse our latest Stem Cells and Regenerative Medicine articles

Zebrafish caudal fin amputation induces an increase in the glycolytic influx that leads to dedifferentiation of osteoblasts and their re-entry in the cell cycle, which is essential for blastema formation and bone regeneration.

Multiple imaging modalities resolved the ultrastructure of single hematopoietic stem cells in their endogenous niche, allowing identification of dopamine beta-hydroxylase positive cells as a functional niche cell type.

A combination of light and electron microscopy has revealed further details about the location and interactions of hematopoietic stem and progenitor cells.

Forward programming of human pluripotent stem cells with a combination of four transcription factors allows the production of functional hepatocytes.

Full spectrum flow cytometry reveals a high degree of placental mesenchymal cell heterogeneity, which is lost with culture, highlighting the importance of detailed ex vivo phenotyping to optimise the use of these cells in downstream applications.

The neonatally maturing pituitary harbors an activated stem cell compartment and shows prominent regenerative capacity, as revealed by single-cell transcriptomic profiling and in vitro (organoid) and in vivo (mouse) exploration.

Interaction of human embryonic stem cells (hESC) with human amniotic epithelial cells (hAEC) confers hESC a pluripotent potential that resembles the anteriorized epiblast, which is predisposed to form the neural ectoderm.

An automated platform for cell culture combines robotics and artificial intelligence to optimize cell culture protocols and reliably produce specific cell types that could be used for regenerative medicine treatments.

Administration of cryopreserved as compared freshly cultured MSCs do not appear to negatively impact measures of in vivo efficacy or in vitro potency in animal models of inflammation.

Genetic complementation approaches in a mouse model of anemia reveals new protein interactions which aid cell survival and promote sensing of environmental cues.