Yucheng Liang, Jean-Emmanuel Hugonnet ... Michel Arthur
The Braun lipoprotein is tethered to peptidoglycan independently from the insertion of newly-synthesized peptidoglycan subunits into the expanding cell wall generating a dynamic equilibrium between free and bound protein forms.
Chileleko Siachisumo, Sara Luzzi ... David J Elliott
A family of RNA binding proteins that diverged 200 million years ago have parallel roles in protecting the transcriptomic integrity of ultra-long exons within their respective cell types.
In a mouse model of Sjogren's disease, mitochondrial function and Ca2+ signaling are disrupted resulting in altered coupling between Ca2+ release and Ca2+ activated Cl- channels and salivary gland hypofunction.
Benjamin R Kop, Yazan Shamli Oghli ... Lennart Verhagen
Realizing the clinical and neuroscientific potential of transcranial ultrasonic stimulation (TUS) requires careful control of the peripheral auditory confounds that underlie previously reported online motor inhibitory effects.
Lisa Baumgartner, Jonathan J Ipsaro ... Julius Brennecke
Genetic and biochemical characterization reveals how a single amino acid change in the chromodomain of the HP1 protein Rhino enables its specific interaction with the guidance factor Kipferl.
Amin MD Shakhawat, Jacqueline G Foltz ... Jennifer L Raymond
The capacity for new cerebellum-dependent learning is influenced by the recent history of neural activity in a mouse model of Fragile X syndrome, suggesting a role for metaplasticity.
Katarzyna Drożdżyk, Martina Peter, Raimund Dutzler
Structural studies revealing the organization of assemblies consisting of CALHM2 and CALHM4 subunits provide insight into the mechanism of heteromerization of large pore channels.
Multiple alleles of Txnip, which can interact with several different proteins, including Hsp90AB1, were tested for their ability to prolong the survival of cone photoreceptors in diseases leading to blindness.
Natalia E Ketaren, Fred D Mast ... John D Aitchison
High-affinity nanobodies targeting the SARS-CoV-2 spike protein demonstrate sustained effectiveness against current and emerging variants, offering a promising avenue for treatment.