Sarah De Beuckeleer, Tim Van De Looverbosch ... Winnok H De Vos
Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
Differentiation of the pathogenic bacterium, Chlamydia trachomatis, from its non-infectious to infectious form is linked to the redox state of the organism.
Aryeh Solomon, Noa Bossel Ben-Moshe ... Roi Avraham
In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.
Nico A Flierman, Sue Ann Koay ... Chris I De Zeeuw
Dentate nucleus neurons can dynamically modulate their activity during a visual attention task, comprising not only sensorimotor but also cognitive attentional components.
The identification of a conserved α-helical domain in monkeypox virus H3 protein as critical for heparan sulfate binding unveils a novel therapeutic target, validated through AI and molecular dynamics simulations, offering potential for broad-spectrum antiviral development.
Low estrogen levels in postmenopausal hypertension are linked to metabolic reprogramming and aortic tissue changes, with L-alpha-aminobutyric acid emerging as a potential protective biomarker.
A naturally acquired human monoclonal antibody recognizes proteins expressed at different stages of the Plasmodium falciparum life cycle through affinity-matured homotypic interactions with glutamate-rich repeats.
Sophie Debaenst, Tamara Jarayseh ... Andy Willaert
Crispant analysis in zebrafish serves as a powerful tool for the rapid functional screening of genes implicated in bone fragility disorders, like osteogenesis imperfecta and osteoporosis.
