Browse our Research Articles

Page 6 of 1,370
    1. Immunology and Inflammation

    Sex-dependent gastrointestinal colonization resistance to MRSA is microbiota and Th17 dependent

    Alannah Lejeune, Chunyi Zhou ... Ken Cadwell
    Gut microbiota composition and sex hormones influence the immune response to methicillin-resistant Staphylococcus aureus gastrointestinal colonization in mice.
    1. Medicine

    Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis

    Marketa Jirouskova, Karel Harant ... Martin Gregor
    A comprehensive proteomic map of liver fibrosis progression and healing in two mouse models identifies etiology-specific extracellular matrix components, laying the foundation for targeted antifibrotic therapies.
    1. Biochemistry and Chemical Biology

    Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida

    Meina He, Yongxin Tao ... Wenli Chen
    Pseudomonas putida coordinates chemotaxis and resistance to copper through the interaction between CheA and CsoR.
    1. Neuroscience

    Effort drives saccade selection

    Damian Koevoet, Laura Van Zantwijk ... Christoph Strauch
    Humans optimize effort expenditure even at the level of eye movements by choosing affordable eye movements over costly alternatives and adjusting gaze behavior based on task demands.
    1. Evolutionary Biology
    2. Neuroscience

    Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice

    Jenny Chen, Phoebe R Richardson ... Hopi E Hoekstra
    Single-nucleus RNA-sequencing of the hypothalamic preoptic area of monogamous and promiscuous deer mouse species reveals neuronal differences that may be responsible for innate changes in mating and parental care behavior.
    1. Immunology and Inflammation
    2. Structural Biology and Molecular Biophysics

    Ab initio prediction of specific phospholipid complexes and membrane association of HIV-1 MPER antibodies by multi-scale simulations

    Colleen A Maillie, Kiana Golden ... Marco Mravic
    Molecular dynamics simulations reveal that lipid binding at antibody loops and framework regions stabilizes membrane interactions, providing molecular details for neutralization mechanisms and strategies for HIV-1 vaccine development.
    1. Microbiology and Infectious Disease

    FtsK is critical for the assembly of the unique divisome complex of the FtsZ-less Chlamydia trachomatis

    McKenna Harpring, Junghoon Lee ... John V Cox
    The novel divisome complex of Chlamydia trachomatis contains elements of the divisome and elongasome from other bacteria, and it requires the chromosomal translocase, FtsK, for its assembly.
    1. Medicine
    2. Neuroscience

    Preclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents

    Ayni Sharif, Matthew S Jeffers ... Manoj M Lalu
    CCR5 antagonists show promise for stroke cerebroprotection and recovery, although further preclinical evidence in clinically relevant domains could strengthen support for clinical translation.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response

    Pavla Nedbalová, Nikola Kaislerova ... Tomáš Doležal
    Adenosine produced by transmethylation may act as a sensor of the balance between cell activity and nutrient supply.
    1. Cancer Biology
    2. Cell Biology

    N6-methyladenosine in DNA promotes genome stability

    Brooke A Conti, Leo Novikov ... Mariano Oppikofer
    Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.