Browse our Short Reports

Page 11 of 60
    1. Genetics and Genomics
    2. Medicine

    Unbiased mosaic variant assessment in sperm: a cohort study to test predictability of transmission

    Martin W Breuss, Xiaoxu Yang ... Joseph G Gleeson
    The abundance of mosaic variants detected directly in sperm accurately predicts their transmission to concepti.
    1. Developmental Biology
    2. Evolutionary Biology

    Gill developmental program in the teleost mandibular arch

    Mathi Thiruppathy, Peter Fabian ... J Gage Crump
    Lineage tracing and genetic analysis in zebrafish show that the pseudobranch is a serial homolog of the gills arising from the jaw-forming mandibular arch, thus supporting the model that vertebrate jaws derived from an ancestral mandibular gill.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Repressing PTBP1 fails to convert reactive astrocytes to dopaminergic neurons in a 6-hydroxydopamine mouse model of Parkinson’s disease

    Weizhao Chen, Qiongping Zheng ... Mingtao Li
    Repressing astroglial PTBP1 by shRNA or antisense oligonucleotide fails to convert astrocyte to neuron including dopaminergic neuron in a 6-OHDA mouse model of PD.
    1. Genetics and Genomics
    2. Neuroscience

    Elevated brain-derived cell-free DNA among patients with first psychotic episode – a proof-of-concept study

    Asael Lubotzky, Ilana Pelov ... Yoav Kohn
    Liquid biopsy methods utilizing brain-specific cell-free DNA methylation markers can detect brain cell death and potentially assist early detection and monitoring of schizophrenia.
    1. Ecology
    2. Microbiology and Infectious Disease

    Humanization of wildlife gut microbiota in urban environments

    Brian A Dillard, Albert K Chung ... Andrew H Moeller
    Urban wildlife harbor gut bacteria found in humans but missing from rural wildlife, consistent with bacterial transmission from humans to wildlife in cities.
    1. Plant Biology

    Perception of a conserved family of plant signalling peptides by the receptor kinase HSL3

    Jack Rhodes, Andra-Octavia Roman ... Cyril Zipfel
    Identification of a new family of stress-induced plant signalling peptides and their cognate receptor.
    1. Neuroscience

    A generalized cortical activity pattern at internally generated mental context boundaries during unguided narrative recall

    Hongmi Lee, Janice Chen
    Prominent transitions between different mental contexts produce a stereotyped brain state shared across internally and externally generated transitions but distinct from minor within-context transitions, potentially reflecting a major flushing and updating of mental models.
    1. Immunology and Inflammation
    2. Structural Biology and Molecular Biophysics

    Structure of the IL-27 quaternary receptor signaling complex

    Nathanael A Caveney, Caleb R Glassman ... K Christopher Garcia
    The cryogenic-electron microscopy structure of IL-27 bound to receptors, IL-27Rα and gp130, revealing a three-site assembly mechanism and overall topology and molecular details reminiscent of IL-6 but distinct from related IL-12 and IL-23.
    1. Ecology

    Regional opportunities for tundra conservation in the next 1000 years

    Stefan Kruse, Ulrike Herzschuh
    The treeline follows climate warming with a severe time lag, but migration rates are increasing so that only under ambitious mitigation efforts will 30% of original tundra areas remain in the north in the long run.
    1. Immunology and Inflammation
    2. Medicine

    The DNA sensors AIM2 and IFI16 are SLE autoantigens that bind neutrophil extracellular traps

    Brendan Antiochos, Daniela Trejo-Zambrano ... Antony Rosen
    A novel extracellular role for cytoplasmic DNA sensors in shielding NET DNA from DNase-mediated degradation.