Browse our latest Cell Biology articles

Page 4 of 310
    1. Cell Biology

    Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis

    Joan Chang, Adam Pickard ... Karl E Kadler
    Secretion and fibrillogenesis of collagen-I are separately controlled molecular pathways in the fibroblast, where surprisingly endocytic recycling is required for fibril formation and is increased in fibrotic fibroblasts.
    1. Cell Biology

    Hypersensitive intercellular responses of endometrial stromal cells drive invasion in endometriosis

    Chun-Wei Chen, Jeffery B Chavez ... Bruce J Nicholson
    A unique functional comparison of the major endometrial cell types from 44 control and endometriosis patients demonstrates not only a uterine origin of the disease, but also that endometrial to mesothelial cell gap junctions are required for invasive lesion formation.
    1. Cell Biology
    2. Genetics and Genomics

    Robust single-nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity

    Jisun So, Olivia Strobel ... Hyun Cheol Roh
    Significant technical improvement in single-nucleus RNA-seq reveals distinct adipocyte subpopulations that respond differently to obesity, including those undergoing adaptive healthy expansion and others displaying severe dysfunction.
    1. Cell Biology

    Aging: Restoring bone healing potential

    Inês Sequeira
    A combination of intermittent fasting and administering Wnt3a proteins to a bone injury can rejuvenate bone repair in aged mice.
    Version of Record
    Insight
    1. Cell Biology

    Glucokinase activity controls peripherally-located subpopulations of β-cells that lead islet Ca2+ oscillations

    Erli Jin, Jennifer K Briggs ... Matthew J Merrins
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Cell Biology

    Emergence of Dip2-mediated Specific DAG-based PKC Signalling Axis in Eukaryotes

    Sakshi Shambhavi, Sudipta Mondal ... Rajan Sankaranarayanan
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cell Biology
    2. Physics of Living Systems

    A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

    David Trombley McSwiggen, Helen Liu ... Hilary P Beck
    Single-molecule tracking at scale, analyzing millions of cells and thousands of compounds per day, demonstrates that measuring protein motion provides mechanistic insights relevant to drug discovery.
    1. Cell Biology
    2. Immunology and Inflammation

    The Human Mitochondrial Genome Encodes for an Interferon-Responsive Host Defense Peptide

    Michelle C Rice, Maria Imun ... Changhan Lee
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Neuroscience

    Dilated cardiomyopathy-associated RNA Binding Motif Protein 20 regulates long pre-mRNAs in neurons

    Giulia Di Bartolomei, Raul Ortiz ... Peter Scheiffele
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling