Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Distinct adaptation and epidemiological success of different genotypes within Salmonella enterica serovar Dublin

    Cheryll M Sia, Rebecca L Ambrose ... Danielle J Ingle
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    1. Immunology and Inflammation
    2. Neuroscience

    A microglia clonal inflammatory disorder in Alzheimer’s disease

    Rocio Vicario, Stamatina Fragkogianni ... Frédéric Geissmann
    A subset of Alzheimer disease patients carry mutant microglia somatic clones which promote neuro-inflammation.
    1. Immunology and Inflammation

    Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions

    Sytse J Piersma, Shasha Li ... Wayne M Yokoyama
    A novel mouse model offers definitive evidence that a single inhibitory receptor family governs the critical natural killer cell functions of licensing and missing-self.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated signaling pathway in humans and mice

    Chong Chen, Qian Liu ... Xinting Liu
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Immunology and Inflammation

    The antigenic landscape of N1 neuraminidase in human influenza A virus strains isolated between 2009 and 2020

    João Paulo Portela Catani, Anouk Smet ... Thorsten U Vogel
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Tissue resident memory CD4+ T cells are sustained by site-specific levels of self-renewal and replacement from precursors

    Jodie Chandler, M Elise Bullock ... Andrew J Yates
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Immunology and Inflammation
    2. Computational and Systems Biology

    Celldetective: an AI-enhanced image analysis tool for unraveling dynamic cell interactions

    Rémy Torro, Beatriz Díaz-Bello ... Laurent Limozin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cancer Biology
    2. Immunology and Inflammation

    Unraveling the power of NAP-CNB’s machine learning-enhanced tumor neoantigen prediction

    Almudena Mendez-Perez, Andres M Acosta-Moreno ... Esteban Veiga
    NAP-CNB, a machine learning platform, accurately identifies tumor neoantigens, where higher tumor expression correlates with optimal antitumor activity, and multiantigen vaccination enhances immune responses.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    Layilin Regulates Treg Motility and Suppressive Capacity in Skin

    Victoire Gouirand, Sean Clancy ... Michael D Rosenblum
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete