Browse our Research Articles

RNA interference pathways are spatially and temporally organized during Caenorhabditis elegans embryogenesis, with the Argonaute protein NRDE-3 playing distinct roles in regulating genes in different cell types and developmental stages.

HIV-1 Vif induces a unique and prolonged pseudo-metaphase arrest by disrupting phosphatase feedback regulation at the kinetochore.

The gut microbiome regulates protein absorption activity in lysosome-rich enterocytes (LREs) and causes broad gene expression changes, while LRE activity also affects the microbiome.

Peptides designed by artificial intelligence restrict both drug-resistant bacteria and rapidly evolving viruses.

Prevention of either lipid uptake or lipid catabolism in infected macrophages restricts the ability of Mycobacterium tuberculosis to grow inside these cells.

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating efficiency.

Congenital deafness increases individual differences in brain connectivity from the auditory cortex, particularly to language-related regions, highlighting how sensory loss shapes brain organization and development and the importance of personalized rehabilitation.

Identification and characterization of enhancers for eight key arterial genes reveal transcription factors associated with different aspects of endothelial gene expression specificity and provide a tool for a better understanding of arterial differentiation.

Genome-wide CRISPR screen identified propionyl-CoA subunit B as a key regulator for anti-tumor T-cell activity in pancreatic cancer, which holds promise for advancing immunotherapy strategies in curing pancreatic cancer.

A fly’s preference for one odor versus another can be predicted by the idiosyncratic activity of neurons early on in the olfactory information processing circuit.